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Minna Mutka

University of Helsinki - Helsinki University Central Hospital

Topeliuksenkatu 5

Helsinki, 00260

Finland

  • University of Helsinki - Helsinki University Central Hospital

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Complex I Drives Glutamine-Dependent TCA Cycle to Support Viability of MYChigh Breast Cancer Cells

Number of pages: 52 Posted: 05 Jun 2025
Johanna M. Anttila, Mariel Savelius, Juhi Somani, Daniel Nicorici, Pauliina M. Munne, Linda Id, Aino Peura, Antti O. Hiltunen, July Aung, Ryan Awadhpersad, Bina Prajapati, Martina Peltonen, Hanna Ala-Hongisto, Prson Gautam, Mika J. Valimaki, Topi A. Tervonen, Karina Sapovalovaite, Raman Devarajan, Maria Victoria Ruiz Perez, Minna Mutka, Panu Kovanen, Laura Niinikoski, Tuomo Meretoja, Johanna Mattson, Paivi Heikkila, Krister Wennerberg, Marie Arsenain-Henriksson, Jukka Westermarck, Tero Aittokallio, Andrei Goga, Christopher B. Jackson, Anni I. Nieminen, Juha Klefstrom and Sneak Peek Administrator
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Abstract:

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cancer, breast cancer, MYC, metabolism, mitochondria, complex I, respiration