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Panu Kovanen

Helsinki University Central Hospital

Topeliuksenkatu 5

Helsinki, 00260

Finland

  • Helsinki University Central Hospital

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Complex I Drives Glutamine-Dependent TCA Cycle to Support Viability of MYChigh Breast Cancer Cells

Number of pages: 52 Posted: 05 Jun 2025
Sneak Peek Administrator, Johanna M. Anttila, Mariel Savelius, Juhi Somani, Daniel Nicorici, Pauliina M. Munne, Linda Id, Aino Peura, Antti O. Hiltunen, July Aung, Ryan Awadhpersad, Bina Prajapati, Martina Peltonen, Hanna Ala-Hongisto, Prson Gautam, Mika J. Valimaki, Topi A. Tervonen, Karina Sapovalovaite, Raman Devarajan, Maria Victoria Ruiz Perez, Minna Mutka, Panu Kovanen, Laura Niinikoski, Tuomo Meretoja, Johanna Mattson, Paivi Heikkila, Krister Wennerberg, Marie Arsenain-Henriksson, Jukka Westermarck, Tero Aittokallio, Andrei Goga, Christopher B. Jackson, Anni I. Nieminen and Juha Klefstrom
Independent, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, University of Helsinki, Karolinska Institutet, University of Helsinki - Helsinki University Central Hospital, University of Helsinki - Helsinki University Central Hospital, Helsinki University Hospital, Helsinki University Hospital, Helsinki University Hospital, University of Helsinki - Helsinki University Central Hospital, University of Copenhagen, Karolinska Institutet - Department of Microbiology, Tumor and Cell Biology (MTC), University of Turku, University of Helsinki - Institute for Molecular Medicine Finland (FIMM), University of California, San Francisco (UCSF) - Department of Cell and Tissue Biology, University of Helsinki, University of Helsinki and University of Helsinki
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Abstract:

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cancer, breast cancer, MYC, metabolism, mitochondria, complex I, respiration