default author photo

Nicolas Guedeney

Université Paris Cité

85 boulevard Saint-Germain

Paris, 75006

France

  • Université Paris Cité

SCHOLARLY PAPERS

2

DOWNLOADS

123

TOTAL CITATIONS

0

Scholarly Papers (2)

Actions:
Email selected abstracts
1.

ID Card of Mcl-1 PROTAC degrader: From in silico design to biological validation in chemoresistant ovarian cancer

Number of pages: 66 Posted: 01 Dec 2025
Marie Cornu, Jocelyn Pezeril, Nicolas Guedeney, Hippolyte Paysant, Thomas Lemaitre, Florian Schwalen, Romane Florent, Julie N’Guyen, Sophie Corvaisier, Marc Since, Dimitri Fayolle, Amina Hamza, Mike Maillasson, Jana Sopkova de Oliveira Santos, Charline Kieffer, Laurent Poulain and anne sophie voisin-chiret
affiliation not provided to SSRN, affiliation not provided to SSRN, Université Paris Cité, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Normandie Université, Normandie Université, Université de Lyon, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN and University of Caen Normandy
Downloads 65 (942,565)

Abstract:

Loading...

PROTAC, Targeted protein degradation, Mcl-1, ovarian cancer, oligopyridine

2.

Synthesis of novel 4-amino-1,5-dihydro-2H-chromeno[2,3-d]pyrimidin-2-one derivatives with diverse substituents

Number of pages: 33 Posted: 28 Jul 2025
Ting Chen, Nicolas Guedeney, Patrick Deschamps, Syrine Mahdadi and stephanie desbène-finck
Université Paris Cité, Université Paris Cité, Université Paris Cité, Université Paris Cité and Université Paris Cité
Downloads 58 (980,173)

Abstract:

Loading...

Chromeno[2, 3-d]pyrimidin-2-one derivatives, Cytosine-based derivatives, Fused heterocycles, Multicomponent reactions, Structure elucidation.