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Natalia V. Ortiz Zacarías

affiliation not provided to SSRN

  • affiliation not provided to SSRN

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Pharmacological Profiling of Antagonists for Cc Chemokine Receptor 5: Evidence for Allosterism, Biased Antagonism and Probe Dependence

Number of pages: 50 Posted: 13 Aug 2025
Yao Yao, Gijs Stavast, Cas van der Horst, Natalia V. Ortiz Zacarías and Laura H. Heitman
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN and Leiden University - Leiden Academic Centre for Drug Research
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Abstract:

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CC chemokine receptor 5, pharmacological profiling, orthosteric antagonist, allosteric antagonist, probe dependence, biased antagonism