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Nathanael S. Gray

Harvard University - Department of Biological Chemistry and Molecular Pharmacology

250 Longwood Avenue

Boston, MA 02115

United States

SCHOLARLY PAPERS

2

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78

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0

Scholarly Papers (2)

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1.

Targeting Vulnerabilities in Successive Cell Cycle Stages to Induce Death of PI3K-Activated Basal-Like Breast Cancer Cells

Number of pages: 63 Posted: 31 Oct 2018
Sameer S. Chopra, Anne Jenney, Adam C. Palmer, Mario Niepel, Caitlin Mills, Sindhu Carmen Sivakumaren, Qingsong Liu, Nathanael S. Gray and Peter K. Sorger
Harvard University - Laboratory of Systems Pharmacology, Harvard University - Laboratory of Systems Pharmacology, Harvard University - Laboratory of Systems Pharmacology, Harvard University - Laboratory of Systems Pharmacology, Harvard University - Laboratory of Systems Pharmacology, Harvard University - Department of Biological Chemistry and Molecular Pharmacology, Harvard University - Department of Biological Chemistry and Molecular Pharmacology, Harvard University - Department of Biological Chemistry and Molecular Pharmacology and Harvard University - Laboratory of Systems Pharmacology
Downloads 45 (1,121,190)

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2.

Catalytic Domain Plasticity of MKK7 Reveals Structural Mechanisms of Allosteric Activation and New Targeting Opportunities

Number of pages: 41 Posted: 23 Apr 2020
Martin Schröder, Li Tan, Jinhua Wang, Yanke Liang, Nathanael S. Gray, Stefan Knapp and Apirat Chaikuad
Goethe University Frankfurt - Institute of Pharmaceutical Chemistry, Dana-Farber Cancer Institute - Department of Cancer Biology, Dana-Farber Cancer Institute - Department of Cancer Biology, Dana-Farber Cancer Institute - Department of Cancer Biology, Harvard University - Department of Biological Chemistry and Molecular Pharmacology, Goethe University Frankfurt - Institute of Pharmaceutical Chemistry and Goethe University Frankfurt - Institute of Pharmaceutical Chemistry
Downloads 33 (1,277,121)

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mitogen-activated protein kinase kinase 7, MKK7, allosteric regulation, kinase activation, kinase inhibitor, covalent inhibitor