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Martin Schröder

Goethe University Frankfurt - Institute of Pharmaceutical Chemistry

Max-von-Laue-Str. 9

Frankfurt, D-60438

Germany

SCHOLARLY PAPERS

2

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78

TOTAL CITATIONS

2

Scholarly Papers (2)

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1.

Structure-Kinetic-Relationship Reveals the Mechanism of Selectivity of FAK Inhibitors Over PYK2

Number of pages: 53 Posted: 14 Aug 2020
Benedict-Tilman Berger, Marta Amaral, Daria B. Kokh, Ariane Nunes-Alves, Djordje Musil, Timo Heinrich, Martin Schröder, Rebecca Neil, Jing Wang, Iva Navratilova, Joerg Bomke, Jonathan M. Elkins, Susanne Müller, Matthias Frech, Rebecca C. Wade and Stefan Knapp
Goethe University Frankfurt - Structural Genomics Consortium, Merck KGaA - Discovery Technologies, Heidelberg Institute for Theoretical Studies (HITS) - Molecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies (HITS) - Molecular and Cellular Modeling Group, Merck KGaA - Discovery Technologies, Merck KGaA - Discovery Technologies, Goethe University Frankfurt - Institute of Pharmaceutical Chemistry, Heidelberg Institute for Theoretical Studies (HITS) - Molecular and Cellular Modeling Group, University of Oxford - Structural Genomics Consortium (SGC), University of Dundee - Division of Biological Chemistry and Drug Discovery, Merck KGaA - Discovery Technologies, University of Oxford - Structural Genomics Consortium (SGC), Goethe University Frankfurt - Structural Genomics Consortium, Merck KGaA - Discovery Technologies, Heidelberg Institute for Theoretical Studies (HITS) - Molecular and Cellular Modeling Group and Goethe University Frankfurt - Institute of Pharmaceutical Chemistry
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2.

Catalytic Domain Plasticity of MKK7 Reveals Structural Mechanisms of Allosteric Activation and New Targeting Opportunities

Number of pages: 41 Posted: 23 Apr 2020
Martin Schröder, Li Tan, Jinhua Wang, Yanke Liang, Nathanael S. Gray, Stefan Knapp and Apirat Chaikuad
Goethe University Frankfurt - Institute of Pharmaceutical Chemistry, Dana-Farber Cancer Institute - Department of Cancer Biology, Dana-Farber Cancer Institute - Department of Cancer Biology, Dana-Farber Cancer Institute - Department of Cancer Biology, Harvard University - Department of Biological Chemistry and Molecular Pharmacology, Goethe University Frankfurt - Institute of Pharmaceutical Chemistry and Goethe University Frankfurt - Institute of Pharmaceutical Chemistry
Downloads 33 (1,277,121)

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mitogen-activated protein kinase kinase 7, MKK7, allosteric regulation, kinase activation, kinase inhibitor, covalent inhibitor