Author Page for Michael Regnier

A Human Variant in the the Troponin Inhibitor3 Switch Domain Causes Diastolic Dysfunction in a Novel Mouse Model

Number of pages: 8 Posted: 05 Mar 2024

University of California, San Diego (UCSD), University of Washington, University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of Washington, University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), Providence St. Vincent Medical Center, Oregon Health and Science University, University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), Cincinnati Children's Hospital Medical Center, University of Washington - Department of Bioengineering, University of California, San Diego (UCSD) and University of California, San Diego (UCSD)

Downloads 78 (823,616)

Abstract:

2.

Dual Role of Tropomyosin-R160 in Thin Filament Regulation: Insights into Phosphorylation-Dependent Cardiac Relaxation and Cardiomyopathy Mechanisms

Number of pages: 23 Posted: 04 Feb 2025

Meaghan E. Barry, Michael Rynkiewicz, Jian Wen, An-Yue Tu, Michael Regnier, William J. Lehman and Jeffrey R. Moore

University of Massachusetts Lowell, Boston University School of Medicine - Department of Physiology & Biophysics, Boston University, University of Washington, University of Washington - Department of Bioengineering, Boston University School of Medicine - Department of Physiology & Biophysics and University of Massachusetts Lowell

Downloads 56 (1,000,027)

Abstract:

3.

Sarcomere Function Inhibits Cardiomyocyte Replication and Promotes Polyploidization Through a DNA Damage Response that Limits In vivo Cell Engraftment

Number of pages: 69 Posted: 27 Jul 2020

Anthony M. Pettinato, Dasom Yoo, Jennifer VanOudenhove, Yu-Sheng Chen, Rachel Cohn, Feria A. Ladha, Xiulan Yang, Ketan Thakar, Robert Romano, Nicolas Legere, Emily Meredith, Paul Robson, Michael Regnier, Justin Cotney, Charles E. Murry and J. Travis Hinson

UConn Health - Department of Genetics and Genome Sciences, University of Washington - Department of Bioengineering, UConn Health - Department of Genetics and Genome Sciences, Jackson Laboratory for Genomic Medicine, Jackson Laboratory for Genomic Medicine, UConn Health - Department of Genetics and Genome Sciences, University of Washington - Institute for Stem Cell and Regenerative Medicine, Jackson Laboratory for Genomic Medicine, Jackson Laboratory for Genomic Medicine, Jackson Laboratory for Genomic Medicine, Jackson Laboratory for Genomic Medicine, The Jackson Laboratory - Jackson Laboratory for Genomic Medicine, University of Washington - Department of Bioengineering, University of Connecticut - Graduate Program in Genetics and Developmental Biology, University of Washington - Department of Bioengineering and UConn Health - Department of Genetics and Genome Sciences

Downloads 48 (1,086,013)

Abstract:

4.

Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model

Number of pages: 50 Posted: 03 Sep 2025

Sonette Steczina, Saffie Mohran, Matthew C. Childers, Timothy McMillen, Ateeqa Naim, Matvey Pilagov, Marica Dente, Kristina B. Kooiker, Christian J. Mandrycky, Khushi Twade, Jennifer Hesson, Jing Zhao, Julie Mathieu, J. Manuel Pioner, Michael A. Geeves, Weikang Ma, Farid Moussavi-Harami, Neil M. Kad and Michael Regnier

Cytokinetics Inc, affiliation not provided to SSRN, University of Washington, University of Washington, University of Kent, University of Kent, University of Florence, affiliation not provided to SSRN, University of Washington, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Florence, University of Kent, Illinois Institute of Technology, affiliation not provided to SSRN, University of Kent and University of Washington - Department of Bioengineering

Downloads 29 (1,332,057)

Michael Regnier

University of Washington - Department of Bioengineering

4

211

0

Scholarly Papers (4)

A Human Variant in the the Troponin Inhibitor3 Switch Domain Causes Diastolic Dysfunction in a Novel Mouse Model

Abstract:

Dual Role of Tropomyosin-R160 in Thin Filament Regulation: Insights into Phosphorylation-Dependent Cardiac Relaxation and Cardiomyopathy Mechanisms

Abstract:

Sarcomere Function Inhibits Cardiomyocyte Replication and Promotes Polyploidization Through a DNA Damage Response that Limits In vivo Cell Engraftment

Abstract:

Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model

Abstract: