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Christian J. Mandrycky

University of Washington

Seattle, WA 98195

United States

  • University of Washington

SCHOLARLY PAPERS

2

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99

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0

Scholarly Papers (2)

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1.

Full-Length Dystrophin Deficiency Leads to Contractile and Calcium Transient Defects in Human Engineered Heart Tissues

Number of pages: 39 Posted: 02 May 2022
Samantha B. Bremner, Christian J. Mandrycky, Andrea Leonard, Ruby M. Padgett, Alan R. Levinson, Ethan S. Rehn, J. Manuel Pioner, Nathan J. Sniadecki and David L. Mack
University of Washington, University of Washington, University of Washington, University of Washington, University of Washington, University of Washington, University of Florence, University of Washington - Department of Bioengineering and University of Washington - Department of Bioengineering
Downloads 70 (875,328)

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Duchenne muscular dystrophy, engineered heart tissue, Human induced pluripotent stem cell-derived cardiomyocytes, disease modeling

2.

Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model

Number of pages: 50 Posted: 03 Sep 2025
Sonette Steczina, Saffie Mohran, Matthew C. Childers, Timothy McMillen, Ateeqa Naim, Matvey Pilagov, Marica Dente, Kristina B. Kooiker, Christian J. Mandrycky, Khushi Twade, Jennifer Hesson, Jing Zhao, Julie Mathieu, J. Manuel Pioner, Michael A. Geeves, Weikang Ma, Farid Moussavi-Harami, Neil M. Kad and Michael Regnier
Cytokinetics Inc, affiliation not provided to SSRN, University of Washington, University of Washington, University of Kent, University of Kent, University of Florence, affiliation not provided to SSRN, University of Washington, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Florence, University of Kent, Illinois Institute of Technology, affiliation not provided to SSRN, University of Kent and University of Washington - Department of Bioengineering
Downloads 29 (1,332,057)

Abstract:

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Cardiac myosincrossbridge cyclinghypertrophic cardiomyopathyhypercontractilitymyosin recruitment