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Matthew C. Childers

University of Washington

SCHOLARLY PAPERS

2

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107

TOTAL CITATIONS

0

Scholarly Papers (2)

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1.

A Human Variant in the the Troponin Inhibitor3 Switch Domain Causes Diastolic Dysfunction in a Novel Mouse Model

Number of pages: 8 Posted: 05 Mar 2024
Jason M. Duran, Kerry Kao, Elizabeth Silver, Sofie Maisel, Aysen Shathaya, Ana Maria Manso, Yusu Gu, Joshua Fong, Chao Chen, Matthew C. Childers, Angel Soto-Hermida, Wei Feng, Yoshitake Cho, Julius Bogomolovas, Jill M. Gelow, Ahmad Masri, Kelly A. Frazer, Robert S. Ross, Ju Chen, Catherine A. Makarewich, Michael Regnier, Paul Bushway and Eric Adler
University of California, San Diego (UCSD), University of Washington, University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of Washington, University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), Providence St. Vincent Medical Center, Oregon Health and Science University, University of California, San Diego (UCSD), University of California, San Diego (UCSD), University of California, San Diego (UCSD), Cincinnati Children's Hospital Medical Center, University of Washington - Department of Bioengineering, University of California, San Diego (UCSD) and University of California, San Diego (UCSD)
Downloads 78 (823,616)

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troponin I, Cardiomyopathy, switch domain, molecular simulation

2.

Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model

Number of pages: 50 Posted: 03 Sep 2025
Sonette Steczina, Saffie Mohran, Matthew C. Childers, Timothy McMillen, Ateeqa Naim, Matvey Pilagov, Marica Dente, Kristina B. Kooiker, Christian J. Mandrycky, Khushi Twade, Jennifer Hesson, Jing Zhao, Julie Mathieu, J. Manuel Pioner, Michael A. Geeves, Weikang Ma, Farid Moussavi-Harami, Neil M. Kad and Michael Regnier
Cytokinetics Inc, affiliation not provided to SSRN, University of Washington, University of Washington, University of Kent, University of Kent, University of Florence, affiliation not provided to SSRN, University of Washington, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Florence, University of Kent, Illinois Institute of Technology, affiliation not provided to SSRN, University of Kent and University of Washington - Department of Bioengineering
Downloads 29 (1,332,057)

Abstract:

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Cardiac myosincrossbridge cyclinghypertrophic cardiomyopathyhypercontractilitymyosin recruitment