default author photo

Darrell N. Kotton

Boston University - Center for Regenerative Medicine

United States

Boston University - Pulmonary Center

Boston, MA

United States

SCHOLARLY PAPERS

3

DOWNLOADS

104

TOTAL CITATIONS

1

Scholarly Papers (3)

1.

Patient-Specific iPSCs Carrying an SFTPC Mutation Reveal the Intrinsic Alveolar Epithelial Dysfunction at the Inception of Interstitial Lung Disease

Number of pages: 86 Posted: 30 Dec 2020
Boston University - Center for Regenerative Medicine, University of Pennsylvania - Division of Pulmonary, Allergy, and Critical Care, University of California, Los Angeles (UCLA) - Department of Medicine, University of California, Los Angeles (UCLA) - Department of Medicine, University of California, Los Angeles (UCLA) - Department of Medicine, Boston University - Center for Regenerative Medicine, Boston University - Center for Regenerative Medicine, University of Pennsylvania - Division of Pulmonary, Allergy, and Critical Care, Boston University - Department of Biochemistry, Boston University - Department of Biochemistry, Boston University - Center for Regenerative Medicine, Boston University - Center for Regenerative Medicine, Vanderbilt University - Department of Pediatrics, Washington University in St. Louis - Division of Newborn Medicine, Washington University in St. Louis - Division of Newborn Medicine, Northwestern University - Department of Pediatrics, Children’s Hospital of Philadelphia - Division of Pulmonary and Sleep Medicine, Boston University - Department of Medicine, Boston University - Department of Biochemistry, Vanderbilt University - Department of Pediatrics, University of California, Los Angeles (UCLA) - Department of Medicine, University of Pennsylvania - Division of Pulmonary, Allergy, and Critical Care and Boston University - Center for Regenerative Medicine
Downloads 55 (1,010,164)
Citation 1

Abstract:

Loading...

induced pluripotent stem cells (iPSCs), iPSC-derived alveolar epithelial type 2 cells (iAEC2s), surfactant protein C (SFTPC), autophagy, proteostasis, bioenergetics, metabolic reprogramming, NF-κB

2.

Human Induced Pluripotent Stem Cell Derived Mesoderm Subset Ameliorates Diabetic Retinopathy by Reestablishing Retinal Function and Restoring Protective Signaling Cascades in Type 2 Diabetes

Number of pages: 81 Posted: 28 Jul 2020
Indiana University - Department of Pediatrics, University of Alabama at Birmingham - Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham - Department of Ophthalmology and Visual Sciences, Indiana University - Department of Pediatrics, University of Alabama at Birmingham - Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham - Department of Ophthalmology and Visual Sciences, Indiana University - Department of Pediatrics, Boston University - Center for Regenerative Medicine, University of Alabama at Birmingham - Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham - Department of Ophthalmology and Visual Sciences, Indiana University - Department of Pediatrics, Indiana University - Department of Microbiology and Immunology, University of Alabama at Birmingham - Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham - Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham - Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham - Department of Ophthalmology and Visual Sciences, Oregon Health and Science University, Konkuk University, Indiana University - Department of Surgery, Boston University - Center for Regenerative Medicine, University of Alabama at Birmingham - Department of Ophthalmology and Visual Sciences, Indiana University - Department of Pediatrics and University of Alabama at Birmingham - Department of Ophthalmology and Visual Sciences
Downloads 37 (1,249,711)

Abstract:

Loading...

3.

A Chimeric Human-Mouse Lung Vascular Model Using Induced Pluripotent Stem Cells Reveals Insights into the Pathogenesis of BMPR2-Related Pulmonary Hypertension

Number of pages: 63 Posted: 26 May 2026
Boston University - Center for Regenerative Medicine, Boston University - Center for Regenerative Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Vanderbilt University, Boston University, Boston University - Center for Regenerative Medicine, University of Pittsburgh, Boston University - Center for Regenerative Medicine and Independent
Downloads 12 (1,555,090)

Abstract:

Loading...

human induced pluripotent stem cells, lung, endothelial, vascular, pulmonary hypertension, CAP1, CAP2, BMPR2, BMP9, cell transplantation, engraftment, H19, lung capillary, AHR signaling, organotypic endothelium