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Lisa R. Young

Children’s Hospital of Philadelphia - Division of Pulmonary and Sleep Medicine

3401 Civic Center Boulevard

Philadelphia, PA 19104

United States

SCHOLARLY PAPERS

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1

Scholarly Papers (1)

1.

Patient-Specific iPSCs Carrying an SFTPC Mutation Reveal the Intrinsic Alveolar Epithelial Dysfunction at the Inception of Interstitial Lung Disease

Number of pages: 86 Posted: 30 Dec 2020
Boston University - Center for Regenerative Medicine, University of Pennsylvania - Division of Pulmonary, Allergy, and Critical Care, University of California, Los Angeles (UCLA) - Department of Medicine, University of California, Los Angeles (UCLA) - Department of Medicine, University of California, Los Angeles (UCLA) - Department of Medicine, Boston University - Center for Regenerative Medicine, Boston University - Center for Regenerative Medicine, University of Pennsylvania - Division of Pulmonary, Allergy, and Critical Care, Boston University - Department of Biochemistry, Boston University - Department of Biochemistry, Boston University - Center for Regenerative Medicine, Boston University - Center for Regenerative Medicine, Vanderbilt University - Department of Pediatrics, Washington University in St. Louis - Division of Newborn Medicine, Washington University in St. Louis - Division of Newborn Medicine, Northwestern University - Department of Pediatrics, Children’s Hospital of Philadelphia - Division of Pulmonary and Sleep Medicine, Boston University - Department of Medicine, Boston University - Department of Biochemistry, Vanderbilt University - Department of Pediatrics, University of California, Los Angeles (UCLA) - Department of Medicine, University of Pennsylvania - Division of Pulmonary, Allergy, and Critical Care and Boston University - Center for Regenerative Medicine
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Citation 1

Abstract:

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induced pluripotent stem cells (iPSCs), iPSC-derived alveolar epithelial type 2 cells (iAEC2s), surfactant protein C (SFTPC), autophagy, proteostasis, bioenergetics, metabolic reprogramming, NF-κB