University of Milan, University of Milan, affiliation not provided to SSRN, affiliation not provided to SSRN, Sapienza University of Rome, Academia Sinica, University of Milan, University of Milan - Department of Biosciences, University of Milan, University of Milan, University of Milan - Department of Biosciences, University of Pavia - Department of Molecular Medicine, University of Pavia, University of Pavia - Department of Molecular Medicine, Sapienza University of Rome, Academia Sinica - Institute of Biological Chemistry, Istituto di Ricerche Farmacologiche Mario Negri IRCCS and University of Milan - Department of Biosciences

University of Milan, University of Milan, University of Pavia, University of Pavia, University of Milan, Academia Sinica, University of Milan - Department of Biosciences, University of Pavia - Department of Molecular Medicine, University of Pavia - Department of Molecular Medicine, University of Pavia, Academia Sinica, University of Milan - Department of Biosciences and Independent

University Hospital Erlangen - Department of Internal Medicine 5, University Hospital Erlangen - Department of Internal Medicine 5, University of Milan - Department of Biosciences, University of Erlangen-Nuremberg-Friedrich Alexander Universität Erlangen Nürnberg - Rheumatology and Immunology, University Hospital Erlangen - Department of Nephropathology, University Hospital Erlangen - Department of Internal Medicine 5, Saarland University - Department of Internal Medicine 1, University Hospital Bonn - Department of Oncology/Hematology and Rheumatology, University Hospital Bonn - Department of Oncology/Hematology and Rheumatology, University of Freiburg - Department of Medicine 1, University of Freiburg - Department of Medicine 1, University Hospital Erlangen - Department of Dermatology, University Hospital Erlangen - Department of Dermatology, Fondazione IRCCS Istituto Neurologico Carlo Besta - Divisione di Neurologia 5 - Neuropatologia, Fondazione IRCCS Istituto Neurologico Carlo Besta - Divisione di Neurologia 5 - Neuropatologia, University Hospital Erlangen - Department of Internal Medicine 5, University Hospital Erlangen - Department of Internal Medicine 5, Friedrich-Alexander-Universität Erlangen-Nürnberg, University Hospital Erlangen - Department of Internal Medicine 5, University of Milan - Department of Biosciences and University Hospital Erlangen - Department of Internal Medicine 5