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Sarita Puri

University of Milan

Via Festa del Perdono, 7

Milan, 20122

Italy

SCHOLARLY PAPERS

3

DOWNLOADS

242

TOTAL CITATIONS

0

Scholarly Papers (3)

1.

The Critical Role of the Variable Domain in Driving Proteotoxicity and Aggregation in Full-Length Light Chains

Number of pages: 43 Posted: 16 Oct 2024
University of Milan, University of Milan, affiliation not provided to SSRN, affiliation not provided to SSRN, Sapienza University of Rome, Academia Sinica, University of Milan, University of Milan - Department of Biosciences, University of Milan, University of Milan, University of Milan - Department of Biosciences, University of Pavia - Department of Molecular Medicine, University of Pavia, University of Pavia - Department of Molecular Medicine, Sapienza University of Rome, Academia Sinica - Institute of Biological Chemistry, Istituto di Ricerche Farmacologiche Mario Negri IRCCS and University of Milan - Department of Biosciences
Downloads 112 (630,858)

Abstract:

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Antibody light chains, AL amyloidosis, Protein structural dynamics, aggregation, soluble toxicity.

2.

N-Glycosylation Multifaceted Effect on κ-Light Chains Associated With AL Amyloidosis

Number of pages: 36 Posted: 14 Oct 2025
University of Milan, University of Milan, University of Pavia, University of Pavia, University of Milan, Academia Sinica, University of Milan - Department of Biosciences, University of Pavia - Department of Molecular Medicine, University of Pavia - Department of Molecular Medicine, University of Pavia, Academia Sinica, University of Milan - Department of Biosciences and Independent
Downloads 65 (924,743)

Abstract:

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N-glycosylation, kappa light chains, systemic AL amyloidosis, protein aggregation

3.

Dimer Dissociation and Aggregation Hot-Spot Exposure Synergistically Accelerate Light Chain Variable Domain Aggregation Associated with Al Amyloidosis

Number of pages: 20 Posted: 16 Jul 2025
University of Milan, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Academia Sinica, affiliation not provided to SSRN, Academia Sinica and University of Milan - Department of Biosciences
Downloads 65 (916,100)

Abstract:

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Cardiotoxic light chains, AL amyloidosis, Protein aggregation, Hydrogen-deuterium exchange mass spectrometry