University of Florence - Department of Experimental and Clinical Medicine, University of Florence - Department of Experimental and Clinical Biomedical Sciences, University of Catania - Faculty of Medicine, University of Florence - Department of Experimental and Clinical Biomedical Sciences, University of Florence - Department of Statistics, Computer Science, Applications, University of Florence - Department of Experimental and Clinical Medicine, University of Florence - Department of Experimental and Clinical Medicine, University of Florence - Department of Experimental and Clinical Medicine, University of Florence - Department of Experimental and Clinical Medicine, NHS Foundation Trust, Royal Free Hospital, University of Milano-Bicocca - School of Medicine and Surgery, University Hospital of Cattinara - Department of Pulmonology, - Department of Translational Medical Sciences, - Department of Translational Medical Sciences, Università Vita-Salute San Raffaele - IRCCS San Raffaele Scientific Institute, Università Vita-Salute San Raffaele - Department of Anesthesia and Intensive Care, University of Florence - Department of Experimental and Clinical Medicine, University of Florence - Department of Experimental and Clinical Medicine, Careggi University Hospital - Department of Clinical and Experimental Medicine, Respiratory Diseases Unit, “San Giuseppe”, University of Florence - Azienda Ospedaliero Universitaria Careggi, University of Florence - Azienda Ospedaliero Universitaria Careggi, Sant’Andrea Hospital, University of Catania - Faculty of Medicine, Rugani Hospital - Radiology Unit, University of Florence - Department of Experimental and Clinical Medicine, University of Florence - Department of Experimental and Clinical Medicine, APHP Hospital Cochin, Careggi University Hospital of Florence - Infectious and Tropical Diseases Unit, University of Trieste - Cattinara Hospital, Università Vita-Salute San Raffaele - IRCCS San Raffaele Scientific Institute, Università Vita-Salute San Raffaele - IRCCS San Raffaele Scientific Institute, - Department of Translational Medical Sciences, IRCCS - Ospedale San Giuseppe MultiMedica - U.O. di Pneumologia, University of Michigan at Ann Arbor - Michigan Scleroderma Program, Nippon Medical School - Department of Allergy and Rheumatology, Università La Sapienza, University of Florence - Department of Experimental and Clinical Medicine, University of Florence - Azienda Ospedaliero Universitaria Careggi, Ca' Foncello General Hospital - Department of Radiology, University of Milano-Bicocca - S. Gerardo Hospital - Respiratory Unit, University of Catania - Faculty of Medicine, University of Florence - Department of Experimental and Clinical Biomedical Sciences and University of Florence - Department of Experimental and Clinical Medicine