Universidad Europea de Madrid - Paediatrics Research Group, Instituto de Investigación 12 de Octubre (imas12) - Pediatric Infectious Diseases Unit, Stellenbosch University - Children’s Infectious Diseases Clinical Research Unit (KID-CRU), University of the Witwatersrand, University College London - Infection, Immunity and Inflammation Research & Teaching Department, Fundação Ariel Glaser contra o SIDA Pediatrico, Centro de Investigação em Saúde da Manhiça (CISM), Centre Hospitalier Universitaire Gabriel Touré, Stellenbosch University - Family Centre for Research with Ubuntu, Fundação Ariel Glaser contra o SIDA Pediatrico, University of the Witwatersrand - Perinatal HIV Research Unit, University of Barcelona - Institut de Salut Global de Barcelona (ISGlobal), Africa Health Research Institute, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Barcelona - Institut de Salut Global de Barcelona (ISGlobal), University of Barcelona - Institut de Salut Global de Barcelona (ISGlobal), Stellenbosch University, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Africa Health Research Institute, Africa Health Research Institute, University of North Carolina (UNC) at Chapel Hill - National Institute of Health, University of Padua - Department of Women’s and Children’s Health, Bambino Gesù Children's Hospital - Academic Department of Pediatrics (DPUO), Columbia University - Irving Medical Center, Bambino Gesù Children's Hospital - Academic Department of Pediatrics (DPUO), University College London Hospitals NHS Foundation Trust - Advanced Pathogen Diagnostics Unit, Ragon Institute of MGH, MIT and Harvard, University College London Hospitals NHS Foundation Trust - Advanced Pathogen Diagnostics Unit, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Bambino Gesù Children's Hospital - Academic Department of Pediatrics (DPUO), affiliation not provided to SSRN, affiliation not provided to SSRN, Stellenbosch University, Stellenbosch University, Africa Health Research Institute, Imperial College London - Department of Paedaitric Infectious Diseases, Stellenbosch University, Baylor College of Medicine, affiliation not provided to SSRN, University of Miami - Miami Center for AIDS Research, affiliation not provided to SSRN, University Hospital 12 de Octubre and Independent

Stellenbosch University - Department of Paediatrics and Child Health, University of California, San Diego (UCSD), University of the Witwatersrand, Stellenbosch University - Children’s Infectious Diseases Clinical Research Unit (KID-CRU), Harvard University - Department of Biostatistics, Harvard University - Department of Biostatistics, University of the Witwatersrand, University of Cape Town - Division of Clinical Pharmacology, Yeshiva University - Jacobi Medical Center, Frontier Science Foundation, National Institutes of Health (NIH) - Division of AIDS, National Institutes of Health (NIH) - Division of Extramural Research, University of the Witwatersrand, Stellenbosch University, Stellenbosch University, Boston University - Chobanian & Avedisian School of Medicine, Chiang Mai University - PHPT/IRD and Independent