Imperial College London - Department of Metabolism, Digestion and Reproduction, University of Exeter - Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, University of Exeter - Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter - IBD Pharmacogenetics Group, Imperial College Healthcare NHS Trust - Department of Medicine & Integrated Care, Imperial College London - Department of Metabolism, Digestion and Reproduction, University of Edinburgh - Centre for Inflammation Research, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Surgery and Cancer, Hull University Teaching Hospitals NHS Trust - Department of Gastroenterology, King’s College London - School of Immunology and Microbial Sciences, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, King's College Hospital - Department of Gastroenterology, University of Cambridge - NIHR BioResource, Cambridge University Hospitals NHS Trust - Department of Gastroenterology, University of Cambridge - NIHR BioResource, Barts Health NHS Trust - Department of Gastroenterology, St George's University Hospitals NHS Foundation Trust - Department of Gastroenterology, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Immunology and Inflammation, Imperial College London, University of Exeter - Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, St Marks Hospital and Academic Institute - Department of Gastroenterology, University of Edinburgh - Centre for Inflammation Research, Royal Devon and Exeter NHS Foundation Trust - Department of Gastroenterology, Imperial College London - Department of Metabolism, Digestion and Reproduction and affiliation not provided to SSRN

Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, St Mark's Hospital, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction and Imperial College London - Department of Metabolism, Digestion and Reproduction

Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Infectious Disease, Imperial College London - Department of Infectious Disease, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, University of Exeter - Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter - IBD Pharmacogenetics Group, Imperial College Healthcare NHS Trust - Department of Medicine & Integrated Care, Imperial College London - Department of Metabolism, Digestion and Reproduction, University of Edinburgh - Centre for Inflammation Research, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Surgery and Cancer, Government of the United Kingdom - Department of Gastroenterology, Guy’s and St. Thomas NHS Foundation Trust - Department of Gastroenterology, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction, King's College Hospital - Department of Gastroenterology, University of Cambridge - NIHR BioResource, University of Cambridge - NIHR BioResource, Barts Health NHS Trust - Department of Gastroenterology, St George's University Hospitals NHS Foundation Trust - Department of Gastroenterology, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Immunology and Inflammation, University of Exeter - Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, St Marks Hospital and Academic Institute - Department of Gastroenterology, NHS Lothian - Department of Gastroenterology, Imperial College London, University of Exeter - Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, Royal Devon and Exeter NHS Foundation Trust - Department of Gastroenterology, Imperial College London - Department of Metabolism, Digestion and Reproduction and Independent

Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Imperial College Healthcare NHS Trust, Imperial College London, Imperial College London, Imperial College London - Department of Metabolism, Digestion and Reproduction, Imperial College London - Department of Metabolism, Digestion and Reproduction and Imperial College London - Department of Metabolism, Digestion and Reproduction