King's College London - Department of Twin Research and Genetic Epidemiology, University of Nottingham - Division of Rheumatology, Orthopaedics and Dermatology, Zoe Global Limited, King’s College London - School of Biomedical Engineering & Imaging Sciences, affiliation not provided to SSRN, affiliation not provided to SSRN, King’s College London - Department of Twin Research and Genetic Epidemiology, Zoe Global Limited, Cedars Sinai Medical Center - Cancer Research Center for Health Equity, affiliation not provided to SSRN, King’s College London - School of Biomedical Engineering & Imaging Sciences, King’s College London - School of Biomedical Engineering & Imaging Sciences, affiliation not provided to SSRN, King’s College London - School of Biomedical Engineering & Imaging Sciences, University College London, affiliation not provided to SSRN, King’s College London - Division of Biomedical Engineering and Imaging Sciences, Zoe Global Limited, Zoe Global Limited, Harvard University - Harvard Medical School, affiliation not provided to SSRN, King’s College London - Department of Twin Research and Genetic Epidemiology, King’s College London - School of Biomedical Engineering & Imaging Sciences and King's College London - Department of Twin Research and Genetic Epidemiology