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Xiaomin Luo
Beijing University of Chinese Medicine - School of Chinese Material Medica
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SCHOLARLY PAPERS
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Scholarly Papers (1)
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1.
Structure-Based Rational Design Enables Discovery of a New Selective and Potent Akt Degrader with Improved Dermatologic Safety
Number of pages: 32
Posted: 14 Mar 2022
Cheng-Liang Zhu
, Xiaomin Luo,
Tian Tian
,
Zijian Rao
,
Hanlin Wang
,
Zhesheng Zhou
,
Zizheng Gao
,
Tian Mi
,
Danni Chen
,
Yongjin Xu
,
Yizhe Wu
,
Jinxin Che
,
Peihua Luo
,
Yubo Zhou
,
Jia Li
and
Xiaowu Dong
Zhejiang University, Beijing University of Chinese Medicine - School of Chinese Material Medica, Zhejiang University, Zhejiang University, Fudan University, Zhejiang University, Zhejiang University, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Zhejiang University, Chinese Academy of Sciences (CAS) - Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Zhejiang University, Zhejiang University, Zhejiang University, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research and Zhejiang University
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Abstract:
AKT, Protein kinase B, PROTAC, Chemical degrader, rational design, Cutaneous toxicity
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