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Xiaomin Luo

Beijing University of Chinese Medicine - School of Chinese Material Medica

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Scholarly Papers (1)

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Structure-Based Rational Design Enables Discovery of a New Selective and Potent Akt Degrader with Improved Dermatologic Safety

Number of pages: 32 Posted: 14 Mar 2022
Zhejiang University, Beijing University of Chinese Medicine - School of Chinese Material Medica, Zhejiang University, Zhejiang University, Fudan University, Zhejiang University, Zhejiang University, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Zhejiang University, Chinese Academy of Sciences (CAS) - Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Zhejiang University, Zhejiang University, Zhejiang University, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research and Zhejiang University
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Abstract:

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AKT, Protein kinase B, PROTAC, Chemical degrader, rational design, Cutaneous toxicity