Heidelberg University Hospital - Division of Infectious Disease and Tropical Medicine, Heidelberg University Hospital - Division of Infectious Disease and Tropical Medicine, Epicentre (Paris), affiliation not provided to SSRN, University College London - Institute for Global Health, University of Nantes - l’institut du thorax, University of Cape Town Lung Institute, affiliation not provided to SSRN, Istituto Superiore di Sanità - Center for Global Health, University of California, San Francisco (UCSF), affiliation not provided to SSRN, UNC Global Projects, affiliation not provided to SSRN, Epicentre (Mbarara), Médecins Sans Frontières - Southern Africa Medical Unit, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Cape Town (UCT), Texas Biomedical Research Institute, Columbia University, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, University of New South Wales (UNSW) - Kirby Institute, University of California, San Francisco (UCSF) - UCSF Center for Tuberculosis, University of Cape Town (UCT) - Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town (UCT) - Division of Clinical Pharmacology, University of Cape Town (UCT) - Institute of Infectious Disease and Molecular Medicine, Stellenbosch University - DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, University of Cape Town (UCT) - Centre for Lung Infection and Immunity, London School of Hygiene & Tropical Medicine and Heidelberg University Hospital - Division of Infectious Disease and Tropical Medicine and German Centre for Infection Research