Leeds Teaching Hospitals NHS Trust, Cardiff University - Centre for Trials Research, University of Leeds - Leeds Institute of Clinical Trials Research, University College London, National Radiotherapy Trials QA (RTTQA) Group, National Radiotherapy Trials QA (RTTQA) Group, Independent, University of Leeds - Leeds Institute of Clinical Trials Research, St James’s University Hospital, University of Leeds - Leeds Institute of Clinical Trials Research, University Hospitals Bristol - University Hospitals Bristol and Weston NHS Foundation Trust, Government of the United Kingdom, Department of Health, National Health Service (NHS), Mount Vernon Cancer Centre Northwood, King’s College London, University College London - Department of Medical Physics and Biomedical Engineering, University Hospitals Sussex NHS Foundation Trust, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, NHS Foundation Trust - Royal Marsden Hospital, The University of Manchester - Manchester Cancer Research Centre, University of Leeds - Institute of Medical Research, University of Leeds, University of Leeds - Leeds Institute of Clinical Trials Research, University of Surrey, University Hospitals Sussex NHS Foundation Trust, Leeds Teaching Hospitals NHS Trust, University of Leeds - Institute of Medical Research and Mount Vernon Hospital

Leeds Teaching Hospitals NHS Trust, University of Oslo - Oslo University Hospital, Maastricht University - GROW School for Oncology and Reproduction, Maastricht University - GROW School for Oncology and Reproduction, Netherlands Cancer Institute Antoni van Leeuwenhoek, Maastricht University, University of New South Wales (UNSW), Catholic University of the Sacred Heart, Rome, Leeds Teaching Hospitals NHS Trust, University of Oslo - Oslo University Hospital, NHS Foundation Trust - Cambridge University Hospitals, Manchester Academic Health Sciences Centre - The Christie NHS Foundation Trust, Goethe University Frankfurt - University Hospital Frankfurt, RWTH Aachen University - University Medical Center Aachen, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, Champalimaud Foundation, Greater Poland Cancer Centre, Government of the United Kingdom - Hull University Teaching Hospitals NHS Trust, Leeds Teaching Hospitals NHS Trust, University of Leeds - Institute of Medical Research, Cardiff University - School of Engineering, Bank of Cyprus Oncology Centre, University of Oslo, Maastricht University - GROW School for Oncology and Reproduction, Leeds Teaching Hospitals NHS Trust and Independent

University of Oxford - MRC Oxford Institute for Radiation Oncology, University of Oxford - MRC Oxford Institute for Radiation Oncology, University of Oxford - MRC Oxford Institute for Radiation Oncology, University of Aberdeen - School of Medicine, University of Aberdeen - School of Medicine, University of Leeds - Institute of Medical Research, Besti Cadwaladr University - North Wales Cancer Treatment Centre, University of Leeds - Leeds Institute of Medical Research at St. James’s, University College London - MRC Clinical Trials Unit, University of Leeds - Institute of Medical Research, University of Leeds - Institute of Medical Research, Queen's University Belfast - Patrick G Johnston Centre for Cancer Research, Wellcome Sanger Institute, University of Oxford - MRC Oxford Institute for Radiation Oncology, University of Oxford - MRC Oxford Institute for Radiation Oncology, University of Oxford - MRC Oxford Institute for Radiation Oncology, University of Oxford - MRC Oxford Institute for Radiation Oncology, Wellcome Sanger Institute - Department of Human Genetics, University Hospital Zurich - Department of Pathology and Molecular Pathology, University of Oxford - Wellcome Trust Centre for Human Genetics, University College London - MRC Clinical Trials Unit, University of Edinburgh - Cancer Research UK Edinburgh Centre, University of Oxford - MRC Oxford Institute for Radiation Oncology, University of Oxford - MRC Oxford Institute for Radiation Oncology and Independent

Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, University of Oxford, University of Oxford, University of Cambridge - Department of Oncology, University College London - UCL Cancer Institute, Manchester Academic Health Sciences Centre - The Christie NHS Foundation Trust, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, University of Oxford - Nuffield Department of Primary Care Health Sciences, University of Oxford, University of Oxford, Velindre Cancer Centre, University Hospitals Bristol - University Hospitals Bristol and Weston NHS Foundation Trust, Imperial College London - Hammersmith Hospital, Department of Cancer Medicine, University of Cambridge, NHS Foundation Trust - Norfolk and Norwich University Hospital, Government of the United Kingdom - Hull University Teaching Hospitals NHS Trust, Coventry University - Coventry University Hospital, Cardiff University - Centre for Trials Research, University of Leeds - Institute of Medical Research, University of Oxford - MRC Oxford Institute for Radiation Oncology, University College London - Department of Medical Physics and Biomedical Engineering and University of Cambridge

University of Oxford, University of Leeds, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, University of Oxford, University of Oxford, University of Leeds, affiliation not provided to SSRN, Oxford University Hospitals NHS Foundation Trust, University of Oxford, The Christie NHS Foundation Trust, University of Oxford - Nuffield Department of Primary Care Health Sciences, University of Oxford, University of Leeds - Institute of Medical Research, University of Leeds and University of Oxford