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Yaming Zhou

Fudan University - Department of Chemistry

SCHOLARLY PAPERS

2

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113

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Scholarly Papers (2)

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1.

Discovery of Novel PI3K/CDK2 Dual Inhibitor Based on 7-Azaindole Derivatives as a Promising Strategy for Triple-Negative Breast Cancer Therapy

Number of pages: 50 Posted: 17 Mar 2023
Chengbin Yang, Menghui Wang, Yimin Gong, Mingli Deng, Yun Ling, Qingquan Li, Jianxin Wang and Yaming Zhou
Fudan University - Department of Pharmaceutics, Fudan University - School of Pharmacy, Fudan University - Department of Chemistry, Fudan University - Department of Chemistry, Fudan University - Department of Chemistry, Fudan University - School of Pharmacy, Fudan University - Department of Pharmaceutics and Fudan University - Department of Chemistry
Downloads 69 (899,324)

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Phosphatidylinositol 3-kinase, Cyclin-dependent kinase, Breast cancer, Azaindole, Dual PI3K/CDK2 inhibitors

2.

Discovery of a High Potent PIM Kinase Inhibitor for Acute Myeloid Leukemia Based on N-Pyridinyl Amide Scaffold by Optimizing the Fragments Toward to Lys67 and Asp128/Glu171

Number of pages: 50 Posted: 24 Apr 2023
Ruiqing Xiang, Mingzhu Lu, Tianze Wu, Chengbin Yang, Yu Jia, Xiaofeng Liu, Mingli Deng, Yu Ge, Jun Xu, Tong Cai, Yun Ling and Yaming Zhou
Fudan University, Fudan University, Fudan University, Fudan University - Department of Pharmaceutics, Fudan University, Fudan University, Fudan University - Department of Chemistry, SD Chem, Inc., ABA Chemicals Corporation, ABA Chemicals Corporation, Fudan University - Department of Chemistry and Fudan University - Department of Chemistry
Downloads 44 (1,145,425)

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N-pyridinyl amide scaffold, PIM inhibitors, Structure-activity relationship, Acute myeloid leukemia