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Ben E. Black

University of Pennsylvania - Department of Biochemistry and Biophysics

SCHOLARLY PAPERS

3

DOWNLOADS

158

TOTAL CITATIONS

0

Scholarly Papers (3)

1.

DNA Pro-Retention Modulators of PARP1 Overcome Primary and Acquired Resistance to Clinical PARP Inhibitors

Number of pages: 48 Posted: 26 Sep 2025
Oregon Health and Science University, Oregon Health and Science University, University of Colorado at Boulder - Department of Biochemistry, University of Montreal, University of Pennsylvania, University of Pennsylvania, University of Pennsylvania, University of Montreal, University of Colorado at Boulder - Department of Biochemistry, University of Montreal, Oregon Health and Science University, Tilikum Therapeutics, Tilikum Therapeutics, Tilikum Therapeutics, Tilikum Therapeutics, Ludwig Maximilian University of Munich (LMU), Ludwig Maximilian University of Munich (LMU), University of Colorado at Boulder - Department of Biochemistry, University of Pennsylvania - Department of Biochemistry and Biophysics, University of Montreal, Oregon Health and Science University and Independent
Downloads 87 (765,566)

Abstract:

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Poly(ADP-ribose) polymerases (PARPs), NAD+-competitive inhibitors, Allosteric regulation, PARP inhibitor resistance, DNA damage response (DDR), Non-enzymatic functions, Synthetic lethality

2.

Centromeric Chromatin Clearings Demarcate the Site of Kinetochore Formation

Number of pages: 76 Posted: 07 May 2024
Kathryn Kixmoeller, Yi-Wei Chang and Ben E. Black
University of Pennsylvania, University of Pennsylvania and University of Pennsylvania - Department of Biochemistry and Biophysics
Downloads 44 (1,133,231)

Abstract:

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Centromere, kinetochore, Mitosis, chromosome, mitotic chromosome, Cryo-ET, chromatin, nucleosome

3.

Centromere-Specifying Nucleosomes Persist in Aging Mouse Oocytes in the Absence of Nascent Assembly

Number of pages: 24 Posted: 27 Apr 2023
University of Pennsylvania - Department of Biology, University of Pennsylvania - Department of Biology, Max Planck Society for the Advancement of the Sciences - Department of Totipotency, Seoul National University - Creative Research Initiatives Center for Epigenetic Code and Diseases, University of Pennsylvania - Department of Biology and University of Pennsylvania - Department of Biochemistry and Biophysics
Downloads 27 (1,359,097)

Abstract:

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centromeres, meiosis, reproductive aging, oocytes