University of Cape Town (UCT), University of Cape Town (UCT), Heidelberg University - University Hospital Heidelberg, the global alliance for diagnostics - FIND, Stellenbosch University - DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, University of Cape Town (UCT) - Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town (UCT) - Wellcome Centre for Infectious Diseases Research in Africa, University of North Carolina Project, Kamazu Central Hospital, University of North Carolina Project, Walter Sisulu University, Heidelberg University Hospital - Division of Infectious Disease and Tropical Medicine, The University of Western Australia - Division of Infection and Immunity, St. George’s University of London, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, University of Cape Town, Walter Sisulu University, Hospital de Porto Alegre, Santa Casa de Misericordia de Porto Alegre, University of Copenhagen - Copenhagen University Hospital, University of Ghana Medical School, University of Basel - Swiss Tropical and Public Health Institute, Ifakara Health Institute, Ifakara Health Institute, University of Basel - Swiss Tropical and Public Health Institute, Aarhus University - Aarhus University Hospital, Aarhus University - Aarhus University Hospital, University of Cape Town (UCT) - Division of Clinical Pharmacology, Stellenbosch University, University of California, San Francisco (UCSF), Stellenbosch University - DST/NRF Centre of Excellence for Biomedical Tuberculosis Research, the global alliance for diagnostics - FIND, Queen Mary University of London, University of Cape Town (UCT) and Imperial College London