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David Burger

Radboud University Nijmegen - Radboud University Medical Center

Nijmegen

Netherlands

SCHOLARLY PAPERS

4

DOWNLOADS

272

TOTAL CITATIONS

0

Scholarly Papers (4)

1.

Trial design and enrolment characteristics of LATA (Long-Acting Treatment in Adolescents): a randomised, open-label, non-inferiority, 96-week trialevaluating the virological efficacy, safety, acceptability and quality-of-life of the dual long-acting injectable regimen (CAB/RPV) compared to daily oral therapy (DTG based TDF or TAF with 3TC or FTC backbone) in virologically suppressed adolescents living with HIV-1 infection, aged 12 to <20 years, in Sub-Saharan Africa

Number of pages: 34 Posted: 30 Oct 2025
affiliation not provided to SSRN, affiliation not provided to SSRN, Joint Clinical Research Centre, Moi University, affiliation not provided to SSRN, Enhancing Care Foundation, University College London - MRC Clinical Trials Unit, Joint Clinical Research Centre, University of Zimbabwe - Clinical Trials Research Centre, Moi University, University of KwaZulu-Natal, Fondazione Penta ETS, affiliation not provided to SSRN, London School of Hygiene & Tropical Medicine - Department of Global Health and Development, Baylor University - Children's Foundation Uganda, Joint Clinical Research Centre, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud University Medical Center, University of York, University College London - Infection, Immunity and Inflammation Research & Teaching Department, University College London - MRC Clinical Trials Unit, Baylor University - Children's Foundation Uganda, affiliation not provided to SSRN, University College London - MRC Clinical Trials Unit, affiliation not provided to SSRN, University College London - MRC Clinical Trials Unit, Baylor University - Children's Foundation Uganda and University College London - MRC Clinical Trials Unit
Downloads 76 (830,555)

Abstract:

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HIV, adolescents, cabotegravir and rilpivirine, antiretroviral therapy, injectable, clinical trial

2.

Short-Cycle Therapy (Weekends-Off) on Dolutegravir-Based Antiretroviral Therapy in Adolescents Living with HIV (BREATHER Plus): A Randomised, Open-Label, 96-Week Non-Inferiority Trial

Number of pages: 29 Posted: 10 Sep 2025
Baylor University - Children's Foundation Uganda, University College London - MRC Clinical Trials Unit, University of Zimbabwe - Clinical Trials Research Centre, Joint Clinical Research Centre, Moi University, University of KwaZulu-Natal, University College London - MRC Clinical Trials Unit, Fondazione Penta ETS, Baylor University - Children's Foundation Uganda, University of Zimbabwe, Joint Clinical Research Centre, Moi University, Enhancing Care Foundation, London School of Hygiene & Tropical Medicine - Department of Global Health and Development, Joint Clinical Research Centre, Baylor University - Children's Foundation Uganda, University of York, Radboud University Nijmegen - Radboud University Medical Center, University of Padua - Department of Women’s and Children’s Health, Baylor University - Children's Foundation Uganda, University of Zimbabwe, Moi University, Enhancing Care Foundation, Fondazione Penta ETS, University College London - MRC Clinical Trials Unit, University College London - MRC Clinical Trials Unit, University College London - Infection, Immunity and Inflammation Research & Teaching Department, University College London - MRC Clinical Trials Unit, University College London - MRC Clinical Trials Unit and University College London - MRC Clinical Trials Unit
Downloads 73 (852,604)

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HIV, adolescents, dolutegravir, short cycle therapy, young people, randomised controlled trial

3.

Development, Validation and Clinical Implementation of a Uplc-Ms/Ms Bioanalytical Method for Simultaneous Quantification of Cabotegravir and Rilpivirine E-Isomer in Human Plasma

Number of pages: 22 Posted: 08 Sep 2023
Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Department of Lung Disease and Radboud University Nijmegen - Radboud University Medical Center
Downloads 66 (907,769)

Abstract:

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cabotegravir, rilpivirine, plasma, light instability, ultra-high performance liquid chromatography, MS/MS detection

4.

Quantification of Dolutegravir, Bictegravir, Raltegravir and Doravirine in Human Breastmilk with Uplc-Ms/Ms

Number of pages: 25 Posted: 15 Apr 2025
affiliation not provided to SSRN, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Department of Lung Disease and Radboud University Nijmegen - Radboud University Medical Center
Downloads 57 (989,921)

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dolutegravir, bictegravir, raltegravir, doravirine, breastmilk, ultra-high performance liquid chromatography, MS/MS detection, HIV, mother-to-child transmission