affiliation not provided to SSRN, The Hospital for Sick Children, University of Alberta, King Abdulaziz University - Faculty of Medicine, affiliation not provided to SSRN, University of Alberta - University of Alberta Hospital, University of Alberta, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Toronto - The Hospital for Sick Children - SickKids, affiliation not provided to SSRN, University of Toronto - The Hospital for Sick Children - SickKids, University of Leeds, affiliation not provided to SSRN, Cornell University - Hospital for Special Surgery, University of Oslo - Oslo University Hospital, affiliation not provided to SSRN, affiliation not provided to SSRN and University of Toronto - The Hospital for Sick Children - SickKids

Maastricht University, Leiden University - Department of Rheumatology, King’s College London - School of Immunology and Microbial Sciences, University of Alberta, Case Western Reserve University, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and LIRMM, University of Leeds and Maastricht University - Department of Internal Medicine