affiliation not provided to SSRN, The Hospital for Sick Children, University of Alberta, King Abdulaziz University - Faculty of Medicine, affiliation not provided to SSRN, University of Alberta - University of Alberta Hospital, University of Alberta, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Toronto - The Hospital for Sick Children - SickKids, affiliation not provided to SSRN, University of Toronto - The Hospital for Sick Children - SickKids, University of Leeds, affiliation not provided to SSRN, Cornell University - Hospital for Special Surgery, University of Oslo - Oslo University Hospital, affiliation not provided to SSRN, affiliation not provided to SSRN and University of Toronto - The Hospital for Sick Children - SickKids

University of Ottawa, The University of Sydney, Johns Hopkins University, Vrije Universiteit Brussel (VUB), Maastricht University - Department of Internal Medicine, Cardiff University, Bispebjerg and Frederiksberg Hospitals - Section for Biostatistics and Evidence-Based Research, University of Leeds, Catholic University of the Sacred Heart of Milan, University of Toronto - The Hospital for Sick Children - SickKids, University of Ottawa - Faculty of Medicine, The Queen Elizabeth Hospital, Patient Research Partner, Patient Research Partner, Leiden University - Leiden University Medical Center (LUMC), National University of Singapore (NUS) - Singapore General Hospital, University of Leeds - Leeds Teaching Hospitals NHS Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, The Ohio State University, University of Ottawa, SDG LLC, University of Toronto, University of Ottawa, University of Ottawa and University of Toronto