affiliation not provided to SSRN, The Hospital for Sick Children, University of Alberta, King Abdulaziz University - Faculty of Medicine, affiliation not provided to SSRN, University of Alberta - University of Alberta Hospital, University of Alberta, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Toronto - The Hospital for Sick Children - SickKids, affiliation not provided to SSRN, University of Toronto - The Hospital for Sick Children - SickKids, University of Leeds, affiliation not provided to SSRN, Cornell University - Hospital for Special Surgery, University of Oslo - Oslo University Hospital, affiliation not provided to SSRN, affiliation not provided to SSRN and University of Toronto - The Hospital for Sick Children - SickKids