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Faissal Imhaouran

VU University Amsterdam

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Scholarly Papers (1)

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Ligand-Directed Biased Agonism at Human Histamine H3 Receptor Isoforms Across Gαi/O- and Β-Arrestin2-Mediated Pathways

Number of pages: 74 Posted: 26 Oct 2023
Sabrina Nalini Rahman, Faissal Imhaouran, Rob Leurs, Arthur Christopoulos, Celine Valant and Christopher J. Langmead
Monash University - Monash Institute of Pharmaceutical Sciences, VU University Amsterdam, VU University Amsterdam, Monash University - Drug Discovery Biology, Monash University - Drug Discovery Biology and Monash University - Monash Institute of Pharmaceutical Sciences
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Abstract:

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G protein-coupled receptors (GPCRs)histamine H3 receptor (H3R)receptor isoformsbiased agonismligand biasneuromodulation