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weixue huang

Chinese Academy of Sciences (CAS) - Shanghai Institute of Organic Chemistry

SCHOLARLY PAPERS

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Scholarly Papers (2)

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1.

Discovery of the First Potent Ror1 Degrader for the Treatment of Non-Small Cell Lung Cancer

Number of pages: 55 Posted: 13 Nov 2024
Fengtao Zhou, Jinlin Li, Lin Li, Caiyun Hou, Zhaodi Tian, Yang Zhou, Jinwei Zhang, xiaomei Ren, Zhen Wang, weixue huang and Ke Ding
Jinan University, Jinan University, Chinese Academy of Sciences (CAS) - Shanghai Institute of Organic Chemistry, Jinan University, Chinese Academy of Sciences (CAS) - Shanghai Institute of Organic Chemistry, Jinan University, Chinese Academy of Sciences (CAS), Chinese Academy of Sciences (CAS) - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CAS), Chinese Academy of Sciences (CAS) - Shanghai Institute of Organic Chemistry and Jinan University
Downloads 52 (1,041,696)

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ROR1, Pseudokinase, PROTACs, Protein Degradation, Apoptosis, Proliferation, NSCLC

2.

Discovery of 5-Aminopyrido[2,3- d]Pyrimidin-7(8 H)-One Derivatives as New Hematopoietic Progenitor Kinase 1 (HPK1) Inhibitors

Number of pages: 61 Posted: 30 Jan 2024
Qiu Xiaorong, Rong Liu, Huan Ling, Yang Zhou, xiaomei Ren, Fengtao Zhou, Jinwei Zhang, weixue huang, Zhen Wang and Ke ding
Chinese Academy of Sciences (CAS) - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CAS) - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CAS) - Shanghai Institute of Organic Chemistry, Jinan University, Chinese Academy of Sciences (CAS) - Shanghai Institute of Organic Chemistry, Jinan University, Chinese Academy of Sciences (CAS), Chinese Academy of Sciences (CAS) - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CAS) and Chinese Academy of Sciences (CAS) - Shanghai Institute of Organic Chemistry
Downloads 44 (1,133,231)

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HPK1, Kinase inhibitor, Cancer immunotherapy, Selectivity, Cocrystal structure