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Laura Fachal

Wellcome Sanger Institute

Hinxton

United Kingdom

SCHOLARLY PAPERS

2

DOWNLOADS

151

TOTAL CITATIONS

0

Scholarly Papers (2)

1.

Clinical Utility and Cost-Effectiveness of Pretreatment NUDT15 Pharmacogenetic Testing to Prevent Thiopurine-Induced Myelosuppression: A Genotype-First Reverse Phenotyping Cohort Study within the UK NIHR Inflammatory Bowel Disease Bioresource

Number of pages: 34 Posted: 07 Mar 2025
University of Exeter - Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Wellcome Sanger Institute, University of Exeter - Royal Devon & Exeter Hospital, NHS Foundation Trust - Cambridge University Hospitals, University of Exeter - Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter - Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter - IBD Pharmacogenetics Group, University of Exeter - Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter - Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, Queen Mary University of London, University of Exeter - Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, St Marks Hospital and Academic Institute, Government of the United Kingdom - Barts Health NHS Trust, Guy’s and St Thomas’ NHS Foundation Trust, Government of the United Kingdom - Royal Wolverhampton NHS Trust, Government of the United Kingdom - Royal Wolverhampton NHS Trust, Northern Care Alliance NHS Group, St Marks Hospital and Academic Institute, Government of the United Kingdom - Hull University Teaching Hospitals NHS Trust, National Institute for Health and Care Research IBD BioResource for Translational Research, Government of the United Kingdom - Department of Gastroenterology, Government of the United Kingdom - Leeds Teaching Hospitals, Guy’s and St. Thomas NHS Foundation Trust - Department of Gastroenterology, Wellcome Sanger Institute, Torbay and South Devon NHS Foundation Trust, Bristol Genetics Laboratory, University of Exeter, University of Exeter, NHS Foundation Trust - Cambridge University Hospitals, University of Exeter - Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group and Royal Devon and Exeter NHS Foundation Trust - Department of Gastroenterology
Downloads 124 (604,538)

Abstract:

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Inflammatory bowel disease, NUDT15, nudix hydrolase 15, TPMT, thiopurine methyltransferase, myelosuppression, thiopurine, azathioprine, mercaptopurine, pharmacogenetics, loop-mediated isothermal amplification, cost effectivness

2.

A Genome-Wide Association Study on Radiation Induced Fibrosis in Breast Cancer Patients

Number of pages: 21 Posted: 19 Mar 2026
Aarhus University - Aarhus University Hospital, Aarhus University - Aarhus University Hospital, University of Cambridge - Centre for Cancer Genetic Epidemiology, University of Cambridge - Department of Oncology, Wellcome Sanger Institute, University of Cambridge - Department of Oncology, University of Cambridge - Centre for Cancer Genetic Epidemiology, Aarhus University - Aarhus University Hospital, Aarhus University, Aarhus University - Aarhus University Hospital and Aarhus University - Aarhus University Hospital
Downloads 27 (1,399,036)

Abstract:

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Radiogenomics, GWAS, radiation-induced morbidity, breast cancer, SNP, Radiotherapy, adverse event, induration, fibrosis, genome-wide association study, single nucleotide polymorphism