affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, CHU de Quebec-Universite Laval, CHU de Quebec-Universite Laval, affiliation not provided to SSRN, CHU de Quebec-Universite Laval, University of Cambridge - Centre for Cancer Genetic Epidemiology, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, CHU de Quebec-Universite Laval, affiliation not provided to SSRN, University of Cambridge - Department of Public Health and Primary Care, affiliation not provided to SSRN, affiliation not provided to SSRN, The University of Manchester - Division of Evolution and Genomic Sciences, affiliation not provided to SSRN, McGill University, University of Toronto - University Health Network, affiliation not provided to SSRN, McGill University - Centre for Genomics and Policy, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, CHU de Quebec-Universite Laval, Université Laval - Department of Molecular Medicine and affiliation not provided to SSRN