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Shelley L. Berger

University of Pennsylvania - Department of Cell and Developmental Biology

3400 Civic Center Blvd

Philadelphia, PA 19104

United States

SCHOLARLY PAPERS

3

DOWNLOADS

1,539

TOTAL CITATIONS

8

Scholarly Papers (3)

1.

Loss of Epigenetic Information as a Cause of Mammalian Aging

Number of pages: 102 Posted: 27 Oct 2021
Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Carnegie Mellon University - Computational Biology Department, Dovetail Genomics, Dovetail Genomics, Dovetail Genomics, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Zymo Research Corporation, Zymo Research Corporation, Zymo Research Corporation, Harvard Medical School - Genetics Division, Harvard University - Paul F. Glenn Center for Biology of Aging Research, University of Pennsylvania - Department of Cell and Developmental Biology, University of Pennsylvania - Department of Cell and Developmental Biology, University of Washington - Division of Nephrology, University of Washington - Division of Nephrology, National Institutes of Health - Experimental Gerontology Section, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, University of California, Santa Cruz - Department of Biomolecular Engineering (BME), Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Carnegie Mellon University - Computational Biology Department, Tokyo Medical and Dental University - Department of Stem Cell Biology, Tokyo Medical and Dental University - Department of Stem Cell Biology, Vium Inc., Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Schepens Eye Research Institute, Harvard Medical School - Schepens Eye Research Institute, Harvard Medical School - The Massachusetts General Hospital Cancer Center, Harvard Medical School - Department of Genetics, Harvard Medical School - Cancer Center, Harvard University - Department of Stem Cell and Regenerative Biology, Keio University - Department of Ophthalmology, University of Nebraska Medical Center - Division of Geriatrics, Gerontology, and Palliative Medicine, Universidade de Coimbra - Department of Life Sciences, Harvard Medical School - Department of Genetics, Harvard Medical School - Department of Genetics, University of Washington - Department of Pathology, Brown University - Department of Molecular Biology, Cell Biology and Biochemistry, Brown University - Department of Molecular Biology, Cell Biology and Biochemistry, Harvard University - Program in Dermatopathology, University of California, Santa Cruz - Department of Biomolecular Engineering (BME), University of Pennsylvania - Department of Cell and Developmental Biology, University of Pennsylvania - Department of Cell and Developmental Biology, National Institutes of Health - Laboratory of Receptor Biology and Gene Expression, University of Washington - Division of Nephrology, Harvard Medical School - Genetics Division, Harvard Medical School - Schepens Eye Research Institute, Carnegie Mellon University - Department of Computational Biology, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research and Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research
Downloads 1,262 (40,523)
Citation 1

Abstract:

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DNA damage, Chromatin, aging, epigenetic clock, epigenetic reprogramming, senescence, RCM (Relocalization of Chromatin Modifiers)

2.

Erosion of the Epigenetic Landscape and Loss of Cellular Identity as a Cause of Aging in Mammals

Number of pages: 104 Posted: 02 Oct 2019
Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Carnegie Mellon University - Computational Biology Department, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Genetics Division, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Carnegie Mellon University - Computational Biology Department, Dovetail Genomics, Dovetail Genomics, Dovetail Genomics, University of Pennsylvania - Department of Cell and Developmental Biology, University of Pennsylvania - Department of Cell and Developmental Biology, University of Washington - Division of Nephrology, University of Washington - Division of Nephrology, University of California, Santa Cruz - Department of Biomolecular Engineering (BME), University of California, Santa Cruz - Department of Biomolecular Engineering (BME), University of Pennsylvania - Department of Cell and Developmental Biology, University of Pennsylvania - Department of Cell and Developmental Biology, National Institutes of Health - Laboratory of Receptor Biology and Gene Expression, University of Washington - Division of Nephrology, Harvard Medical School - Genetics Division, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Carnegie Mellon University - Department of Computational Biology and Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research
Downloads 207 (368,123)
Citation 7

Abstract:

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DNA damage, chromatin, aging, epigenetic clock, histone modification, RCM(Relocalization of Chromatin Modifiers)

3.

In vivo CRISPR Screening Identifies Fli1 as a Transcriptional Safeguard that Restrains Effector CD8 T Cell Differentiation During Infection and Cancer

Number of pages: 70 Posted: 26 May 2020
University of Pennsylvania - Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania - Department of Cancer Biology, University of Pennsylvania - Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania - Epigenetics Institute, University of Pennsylvania - Department of Systems Pharmacology and Translational Therapeutics, Johns Hopkins University - Department of Biomedical Engineering, University of Pennsylvania - Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania - Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania - Department of Cancer Biology, University of Pennsylvania - Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania - Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania - Department of Cancer Biology, University of Pennsylvania - Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania - Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania - Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania - Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania - Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania - Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania - Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania - Department of Cancer Biology, University of Pennsylvania - Department of Cell and Developmental Biology, Johns Hopkins University - Department of Biomedical Engineering, University of Pennsylvania - Department of Cell and Developmental Biology, University of Pennsylvania - Institute for Immunology and University of Pennsylvania - Institute for Immunology
Downloads 70 (875,328)

Abstract:

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CD8 T cell, effector T cell response, in vivo genetic screening, CRISPR, transcription factors, Fli1