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Luis A. Rajman

Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research

United States

SCHOLARLY PAPERS

4

DOWNLOADS

1,952

TOTAL CITATIONS

10

Scholarly Papers (4)

1.

Loss of Epigenetic Information as a Cause of Mammalian Aging

Number of pages: 102 Posted: 27 Oct 2021
Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Carnegie Mellon University - Computational Biology Department, Dovetail Genomics, Dovetail Genomics, Dovetail Genomics, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Zymo Research Corporation, Zymo Research Corporation, Zymo Research Corporation, Harvard Medical School - Genetics Division, Harvard University - Paul F. Glenn Center for Biology of Aging Research, University of Pennsylvania - Department of Cell and Developmental Biology, University of Pennsylvania - Department of Cell and Developmental Biology, University of Washington - Division of Nephrology, University of Washington - Division of Nephrology, National Institutes of Health - Experimental Gerontology Section, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, University of California, Santa Cruz - Department of Biomolecular Engineering (BME), Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Carnegie Mellon University - Computational Biology Department, Tokyo Medical and Dental University - Department of Stem Cell Biology, Tokyo Medical and Dental University - Department of Stem Cell Biology, Vium Inc., Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Schepens Eye Research Institute, Harvard Medical School - Schepens Eye Research Institute, Harvard Medical School - The Massachusetts General Hospital Cancer Center, Harvard Medical School - Department of Genetics, Harvard Medical School - Cancer Center, Harvard University - Department of Stem Cell and Regenerative Biology, Keio University - Department of Ophthalmology, University of Nebraska Medical Center - Division of Geriatrics, Gerontology, and Palliative Medicine, Universidade de Coimbra - Department of Life Sciences, Harvard Medical School - Department of Genetics, Harvard Medical School - Department of Genetics, University of Washington - Department of Pathology, Brown University - Department of Molecular Biology, Cell Biology and Biochemistry, Brown University - Department of Molecular Biology, Cell Biology and Biochemistry, Harvard University - Program in Dermatopathology, University of California, Santa Cruz - Department of Biomolecular Engineering (BME), University of Pennsylvania - Department of Cell and Developmental Biology, University of Pennsylvania - Department of Cell and Developmental Biology, National Institutes of Health - Laboratory of Receptor Biology and Gene Expression, University of Washington - Division of Nephrology, Harvard Medical School - Genetics Division, Harvard Medical School - Schepens Eye Research Institute, Carnegie Mellon University - Department of Computational Biology, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research and Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research
Downloads 1,264 (40,523)
Citation 1

Abstract:

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DNA damage, Chromatin, aging, epigenetic clock, epigenetic reprogramming, senescence, RCM (Relocalization of Chromatin Modifiers)

2.

DNA Break-Induced Epigenetic Drift as a Cause of Mammalian Aging

Number of pages: 97 Posted: 08 Oct 2019
Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Zymo Research Corporation, Zymo Research Corporation, Zymo Research Corporation, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, National Institutes of Health - Experimental Gerontology Section, Tokyo Medical and Dental University - Department of Stem Cell Biology, Tokyo Medical and Dental University - Department of Stem Cell Biology, Vium Inc., Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Schepens Eye Research Institute, Harvard Medical School - Schepens Eye Research Institute, Harvard Medical School - Cancer Center, Harvard University - Harvard Medical School, Harvard Medical School - Cancer Center, Harvard University - Department of Stem Cell and Regenerative Biology, Keio University - Department of Ophthalmology, University of Nebraska Medical Center - Division of Geriatrics, Gerontology, and Palliative Medicine, Universidade de Coimbra - Department of Life Sciences, Harvard Medical School - Department of Genetics, Harvard Medical School - Department of Genetics, University of Washington - Department of Pathology, Brown University - Department of Molecular Biology, Cell Biology and Biochemistry, Brown University - Department of Molecular Biology, Cell Biology and Biochemistry, Harvard Medical School - Program in Dermatopathology, National Institutes of Health - Laboratory of Receptor Biology and Gene Expression, Harvard Medical School - Schepens Eye Research Institute, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research and Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research
Downloads 349 (214,990)
Citation 2

Abstract:

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DNA damage, chromatin, aging, epigenetic clock, histone modification, RCM(Relocalization of Chromatin Modifiers)

3.

Erosion of the Epigenetic Landscape and Loss of Cellular Identity as a Cause of Aging in Mammals

Number of pages: 104 Posted: 02 Oct 2019
Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Carnegie Mellon University - Computational Biology Department, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Genetics Division, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Carnegie Mellon University - Computational Biology Department, Dovetail Genomics, Dovetail Genomics, Dovetail Genomics, University of Pennsylvania - Department of Cell and Developmental Biology, University of Pennsylvania - Department of Cell and Developmental Biology, University of Washington - Division of Nephrology, University of Washington - Division of Nephrology, University of California, Santa Cruz - Department of Biomolecular Engineering (BME), University of California, Santa Cruz - Department of Biomolecular Engineering (BME), University of Pennsylvania - Department of Cell and Developmental Biology, University of Pennsylvania - Department of Cell and Developmental Biology, National Institutes of Health - Laboratory of Receptor Biology and Gene Expression, University of Washington - Division of Nephrology, Harvard Medical School - Genetics Division, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Carnegie Mellon University - Department of Computational Biology and Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research
Downloads 207 (368,123)
Citation 7

Abstract:

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DNA damage, chromatin, aging, epigenetic clock, histone modification, RCM(Relocalization of Chromatin Modifiers)

4.

Long-Term NMN Treatment Increases Lifespan and Healthspan in Mice in a Sex Dependent Manner

Number of pages: 59 Posted: 10 Jun 2024
Harvard University - Paul F. Glenn Center for Biology of Aging Research, Brown University, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Institute for Systems Biology, Institute for Systems Biology, Princeton University, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, Harvard University - Paul F. Glenn Center for Biology of Aging Research, University of Pennsylvania - Perelman School of Medicine, ETH Zürich - Department of Health Sciences and Technology, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Government of the United States of America - Translational Gerontology Branch, University of Washington - Center for Microbiome Science & Therapeutics, University of New South Wales (UNSW), University of Texas Health Science Center at San Antonio, University of Pennsylvania - Perelman School of Medicine, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research and Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research
Downloads 132 (551,165)

Abstract:

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NMN, NAD+, frailty, healthspan, lifespan, mouse models, sex differences, males, females, longevity, metabolomics, microbiome, metabolism