International Centre for Diarrheal Disease Research (icddr,b), Johns Hopkins University - Department of Epidemiology, International Centre for Diarrheal Disease Research (icddr,b), International Centre for Diarrheal Disease Research (icddr,b), International Centre for Diarrheal Disease Research (icddr,b), International Centre for Diarrheal Disease Research (icddr,b), International Centre for Diarrheal Disease Research (icddr,b), Crown Agents, World Hope International, Crown Agents, ICAP – Columbia University, Government of Mali - Centre pour le Développement des Vaccins, Government of Mali - Centre pour le Développement des Vaccins, - Department of Pediatrics, - Center for Vaccine Development and Global Health, - Department of Pediatrics, Chris Hani Baragwanath Academic Hospital - Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand - South African Medical Research Council, University of the Witwatersrand, University of the Witwatersrand, University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, Kenya Medical Research Institute (KEMRI), Kisumu County Department of Health, Kenya Medical Research Institute (KEMRI), Kenya Medical Research Institute (KEMRI), Kisumu County Department of Health, Centro de Investigação em Saúde da Manhiça (CISM), University of Barcelona - Institut de Salut Global de Barcelona (ISGlobal), University of Barcelona - Institut de Salut Global de Barcelona (ISGlobal), Centro de Investigação em Saúde da Manhiça (CISM), Centro de Investigação em Saúde da Manhiça (CISM), Haramaya University - College Health and Medical Science, London School of Hygiene & Tropical Medicine, London School of Hygiene & Tropical Medicine - Department of Infectious Disease and Epidemiology, Mekelle University, Addis Ababa University, Emory University - Emory Global Health Institute, Emory University - Emory Global Health Institute, Government of the United States of America - Centers for Disease Control and Prevention (CDC), Emory University - Emory Global Health Institute, Emory University - Emory Global Health Institute, International Centre for Diarrheal Disease Research (icddr,b) and Independent

Emory University - Rollins School of Public Health, Johns Hopkins University - Bloomberg School of Public Health, Johns Hopkins University - Bloomberg School of Public Health, Johns Hopkins University - International Vaccine Access Center, Johns Hopkins University - Department of Epidemiology, Johns Hopkins University - Bloomberg School of Public Health, Johns Hopkins University - Bloomberg School of Public Health, Johns Hopkins University - Department of International Health, International Vaccine Access Center, World Health Organization (WHO) - Department of Immunizations, Vaccines and Biologicals, University of the Witwatersrand - Department of Clinical Microbiology and Infectious Diseases, RWTH Aachen University - RWTH University Hospital Aachen, University of Amsterdam - Department of Medical Microbiology and Infection Prevention, Consejería de Sanidad - Servicio de Epidemiología, Yale University - Institute for Global Health, affiliation not provided to SSRN, Centers for Disease Control & Prevention - National Center for Immunization and Respiratory Diseases, Centre Hospitalier Intercommunal de Créteil, Statens Serums Institut - Infectious Disease Epidemiology & Prevention, University of West Attica, National Institute of Public Health, affiliation not provided to SSRN, World Health Organization (WHO), Government of the United Kingdom - NHS Greater Glasgow and Clyde, London School of Hygiene & Tropical Medicine, Epiconcept, Riga Stradins University, University of Melbourne - Murdoch Children's Research Institute, World Health Organization (WHO), Toyama Institute of Health - Department of Bacteriology, Tampere University - Faculty of Social Sciences, INEI - ANLIS “Dr. Carlos G. Malbrán" - Servicio de Bacteriología Clínica, World Health Organization’s Regional Office for Africa, Hospital Sant Joan de Deu - Molecular Microbiology Department, Public Health Agency of Sweden, Australian Government - Centre for Disease Control, University of Toronto, Regional Authority of Public Health - National Reference Centre for Pneumococcal and Haemophilus Diseases, London School of Hygiene & Tropical Medicine - Medical Research Council Unit: The Gambia, LACEN - Laboratório Central de Saúde Pública, Public Health England - Immunisation and Countermeasures Division, Landspitali - The National University Hospital - Department of Clinical Microbiology, National Institute of Public Health, National Health Laboratory Services (NHLS) - Centre for Respiratory Diseases and Meningitis, Kaiser Permanente Northern California - Kaiser Permanente Vaccine Study Center, University of Calgary, The University of Sydney, The University of Hong Kong - Department of Microbiology, University of Bern, Government of the United States of America - Arctic Investigations Program, Johns Hopkins University - Department of International Health, International Vaccine Access Center, National Institute of Public Health, ESR (Institute of Environmental Science and Research) - Health Intelligence Team, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, University of Liverpool, Mohammed VI University of Health Sciences, KU Leuven - University Hospitals Leuven, Université Laval, Statens Serums Institut, Ben-Gurion University of the Negev - Faculty of Health Science, Children’s Health Ireland at Temple Street - Irish Meningitis and Sepsis Reference Laboratory, European Centre for Disease Prevention and Control, Instituto Costarricense de Investigación y Enseñanza en Nutrición y Salud, Instituto de Salud Pública y Laboral de Navarra, Italian National Institute of Health, National Centre for Infectious Diseases (Singapore), University of Utah Health Sciences Center - Division of Pediatric Infectious Diseases, Instituto Adolfo Lutz, Instituto de Salud Pública de Chile, Johns Hopkins University - Department of International Health, International Vaccine Access Center and Independent

Johns Hopkins University - Bloomberg School of Public Health, Johns Hopkins University - Department of International Health, International Vaccine Access Center, University of Oxford - KEMRI-Coast Centre for Geographical Medicine and Research, Emory University - Rollins School of Public Health, Johns Hopkins University - Department of Epidemiology, Johns Hopkins University - Bloomberg School of Public Health, Johns Hopkins University - Bloomberg School of Public Health, University of Massachusetts Worcester - UMass Chan Medical School, Johns Hopkins University - Bloomberg School of Public Health, World Health Organization (WHO) - Department of Immunizations, Vaccines and Biologicals, Yale University - Institute for Global Health, OsloMet - Oslo Metropolitan University - Faculty of Health Sciences, University of the Witwatersrand - Department of Clinical Microbiology and Infectious Diseases, Santé Publique France, RWTH Aachen University - RWTH University Hospital Aachen, Statens Serums Institut - Infectious Disease Epidemiology & Prevention, Mie National Hospital, National Institute for Public Health and Environment, National Medicines Institute, National Institute of Public Health, London School of Hygiene & Tropical Medicine, Epiconcept, Riga Stradins University, Rey Juan Carlos University, University of Melbourne - Murdoch Children's Research Institute, University of Calgary, Institute of Public Health of Chile - National Agency for Medical Devices, Innovation and Development (ANDID), Tampere University - Faculty of Social Sciences, Health Protection Surveillance Centre (HPSC), Australian Government - Centre for Disease Control, University of Toronto, Regional Authority of Public Health - National Reference Centre for Pneumococcal and Haemophilus Diseases, London School of Hygiene & Tropical Medicine - Medical Research Council Unit: The Gambia, Government of the United Kingdom - Public Health Scotland, Public Health Agency of Sweden, Public Health England - Immunisation and Countermeasures Division, Landspitali - The National University Hospital - Department of Clinical Microbiology, National Institute of Public Health, Kaiser Permanente Northern California - Kaiser Permanente Vaccine Study Center, The University of Sydney, The University of Hong Kong - Department of Microbiology, University of Bern, University of Malawi - Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Child Health Research Foundation, Johns Hopkins University - Department of International Health, International Vaccine Access Center, Carlos III Institute of Health - CIBER de Epidemiología y Salud Pública (CIBERESP), National Institute of Public Health, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, National Public Health Organization, Athens, affiliation not provided to SSRN, Mohammed VI University of Health Sciences, KU Leuven - University Hospitals Leuven, Université Laval, Ben-Gurion University of the Negev - Faculty of Health Science, European Centre for Disease Prevention and Control, National Health Laboratory Services (NHLS) - Centre for Respiratory Diseases and Meningitis, Generalitat de Catalunya, Ministry of Health, Oman, Kenya Medical Research Institute (KEMRI), Italian National Institute of Health, Government of the United States of America - National Center for Emerging and Zoonotic Infectious Diseases, Instituto Adolfo Lutz, Kenya Medical Research Institute (KEMRI), University of Utah Health Sciences Center - Division of Pediatric Infectious Diseases, Johns Hopkins University - Department of International Health, International Vaccine Access Center, Johns Hopkins University - International Vaccine Access Center and Independent

University of the Witwatersrand - South African Medical Research Council, Global Health Center, Centers for Disease Control and Prevention, Global Health Center, Centers for Disease Control and Prevention, Crown Agents, ICAP – Columbia University, Aberdeen Women’s Centre, UNICEF Sierra Leone, Caritas International-Sierra Leone, University of Barcelona - Institut de Salut Global de Barcelona (ISGlobal), Centro de Investigação em Saúde da Manhiça (CISM), Centro de Investigação em Saúde da Manhiça (CISM), Maputo Central Hospital - Department of Pathology, Centro de Investigação em Saúde da Manhiça (CISM), Government of Mali - Centre pour le Développement des Vaccins, - Department of Pediatrics, - Department of Pediatrics, Government of Mali - Centre pour le Développement des Vaccins, Government of Mali - Centre pour le Développement des Vaccins, Kisumu County Department of Health, Centers for Disease Control and Prevention (Kenya), Kenya Medical Research Institute (KEMRI) - Centre for Global Health Research, Centers for Disease Control & Prevention - National Center for Immunization and Respiratory Diseases, Aga Khan University - Department of Pathology, London School of Hygiene & Tropical Medicine, Haramaya University - College Health and Medical Science, London School of Hygiene & Tropical Medicine - Department of Infectious Disease and Epidemiology, Addis Ababa Burn, Emergency and Trauma Hospital - Department of Microbiology, Haramaya University - College Health and Medical Science, International Centre for Diarrheal Disease Research (icddr,b), International Centre for Diarrheal Disease Research (icddr,b), International Centre for Diarrheal Disease Research (icddr,b), International Centre for Diarrheal Disease Research (icddr,b), International Centre for Diarrheal Disease Research (icddr,b), University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand - School of Pathology, Emory University - Emory Global Health Institute, Emory University - Emory Global Health Institute, University of the Witwatersrand - Wits Infectious Diseases and Oncology Research Institute and University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit

London School of Hygiene & Tropical Medicine, Haramaya University, Haramaya University - Department of Medical Laboratory Sciences, Universitas Pelita Harapan, Haramaya University, Haramaya University, London School of Hygiene & Tropical Medicine, Haramaya University, Haramaya University - College Health and Medical Science, Haramaya University, Haramaya University - College Health and Medical Science, London School of Hygiene & Tropical Medicine, London School of Hygiene & Tropical Medicine and London School of Hygiene & Tropical Medicine - Department of Infectious Disease and Epidemiology

London School of Hygiene & Tropical Medicine, London School of Hygiene & Tropical Medicine, University of Geneva - Geneva University Hospitals, London School of Hygiene & Tropical Medicine, Haramaya University, University of Ghana Medical School, University of Ghana, University of Oxford - KEMRI-Coast Centre for Geographical Medicine and Research, University of Oxford - KEMRI-Coast Centre for Geographical Medicine and Research, Liverpool School of Tropical Medicine, Kamuzu University of Health Sciences, Liverpool School of Tropical Medicine, National Hospital Abuja, National Hospital Abuja, National Hospital Abuja, Stellenbosch University - Department of Paediatrics and Child Health, Kilimanjaro Christian Medical University College - Kilimanjaro Christian Medical Centre, Kilimanjaro Christian Medical University College - Kilimanjaro Christian Medical Centre, Ministry of Health Zambia, Centre for Infectious Disease Research in Zambia, London School of Hygiene & Tropical Medicine, Stellenbosch University, Haramaya University, Haramaya University - College Health and Medical Science, Haramaya University, London School of Hygiene & Tropical Medicine - Department of Infectious Disease and Epidemiology, Haramaya University, Korle Bu Teaching Hospital, University of Ghana Medical School, Korle Bu Teaching Hospital, University of Oxford - KEMRI-Coast Centre for Geographical Medicine and Research, University of Oxford - KEMRI-Coast Centre for Geographical Medicine and Research, Kamuzu University of Health Sciences, Liverpool School of Tropical Medicine - Department of Clinical Sciences, Kamuzu University of Health Sciences, National Hospital Abuja, National Hospital Abuja, Stellenbosch University, Stellenbosch University, Stellenbosch University, Kilimanjaro Christian Medical University College - Kilimanjaro Clinical Research Institute, Kilimanjaro Christian Medical University College, Ministry of Health Zambia, Centre for Infectious Disease Research in Zambia, Ministry of Health Zambia and Right to Care - Zambia

affiliation not provided to SSRN, Kenya Medical Research Institute (KEMRI), Kenya Medical Research Institute (KEMRI), London School of Hygiene & Tropical Medicine - Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, affiliation not provided to SSRN, affiliation not provided to SSRN, Bayero University, affiliation not provided to SSRN, affiliation not provided to SSRN, Kenya Medical Research Institute (KEMRI), Kenya Medical Research Institute (KEMRI), Kenya Medical Research Institute (KEMRI), Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme and London School of Hygiene & Tropical Medicine

University of the Witwatersrand, University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, Government of the United States of America - Centers for Disease Control and Prevention (CDC), University of the Witwatersrand, University of the Witwatersrand, Haramaya University - College Health and Medical Science, London School of Hygiene & Tropical Medicine - Department of Infectious Disease and Epidemiology, Haramaya University - Department of Medical Laboratory Sciences, London School of Hygiene & Tropical Medicine, University of Calabar (UNICAL) - Department of English & Literary Studies, Crown Agents, ICAP – Columbia University, World Health Organization (WHO), - Department of Pediatrics, Government of Mali - Centre pour le Développement des Vaccins, - Department of Pediatrics, Government of Mali - Centre pour le Développement des Vaccins, Centro de Investigação em Saúde de Manhiça, Centro de Investigação em Saúde da Manhiça (CISM), Centro de Investigação em Saúde da Manhiça (CISM), Centro de Investigação em Saúde da Manhiça (CISM), University of Barcelona - Institut de Salut Global de Barcelona (ISGlobal), International Centre for Diarrheal Disease Research (icddr,b), International Centre for Diarrheal Disease Research (icddr,b), International Centre for Diarrheal Disease Research (icddr,b), International Centre for Diarrheal Disease Research (icddr,b), International Centre for Diarrheal Disease Research (icddr,b), Government of the United States of America - Centers for Disease Control and Prevention (CDC), Government of the United States of America - Centers for Disease Control and Prevention (CDC), Kisumu County Department of Health, Emory University - Emory Global Health Institute, Emory University - Emory Global Health Institute, University of Barcelona - Institut de Salut Global de Barcelona (ISGlobal), University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit and Independent