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Peppi Koivunen

University of Oulu - Biocenter Oulu

Oulu

Finland

SCHOLARLY PAPERS

2

DOWNLOADS

111

TOTAL CITATIONS

0

Scholarly Papers (2)

1.

The Jumonji-C Histone Lysine Demethylase KDM3B Senses Cellular Iron to Regulate Anabolism Through mTORC1

Number of pages: 61 Posted: 24 Jun 2021
Northwestern University - Feinberg Cardiovascular Research Institute, Northwestern University - Feinberg Cardiovascular Research Institute, Northwestern University - Department of Biochemistry and Molecular Genetics, Northwestern University - Feinberg Cardiovascular Research Institute, Northwestern University - Department of Biochemistry and Molecular Genetics, Northwestern University - Feinberg Cardiovascular Research Institute, Northwestern University - Feinberg Cardiovascular Research Institute, Northwestern University - Feinberg Cardiovascular Research Institute, Northwestern University - The Chemistry of Life Processes Institute, Northwestern University - Feinberg Cardiovascular Research Institute, Sapporo Medical University - Department of Cellular Physiology and Signal Transduction, Instituto de Agroquímica y Tecnología de Alimentos - Departamento de Biotecnología, Instituto de Agroquímica y Tecnología de Alimentos - Departamento de Biotecnología, Universitat de València - Departamento de Bioquímica y Biología Molecular, University of Chicago - Department of Ecology and Evolution, University of Oulu - Biocenter Oulu, Northwestern University - Department of Biochemistry and Molecular Genetics, Northwestern University - Robert H. Lurie Comprehensive Cancer Center, University of Alberta - Cardiovascular Research Centre, Northwestern University - Department of Biochemistry and Molecular Genetics, Northwestern University - The Chemistry of Life Processes Institute, Northwestern University - Department of Biochemistry and Molecular Genetics, Instituto de Agroquímica y Tecnología de Alimentos - Departamento de Biotecnología, University of Chicago - Department of Ecology and Evolution, University of Oulu - Biocenter Oulu and Northwestern University - Feinberg Cardiovascular Research Institute
Downloads 69 (883,195)

Abstract:

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Iron, epigenetics, histone demethylase, mTOR, amino acids, metabolism, cancer

2.

Title: (R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Tumorigenesis in IDH-Mutant Cancers

Number of pages: 65 Posted: 22 Dec 2021
Harvard University - Dana-Farber Cancer Institute, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Duke University, affiliation not provided to SSRN, University of Utah, Broad Institute, Harvard University - Dana-Farber Cancer Institute, University of California, Los Angeles (UCLA) - Department of Psychiatry and Biobehavioral Sciences, affiliation not provided to SSRN, Duke University, affiliation not provided to SSRN, University of Oulu - Biocenter Oulu and Harvard University - Dana-Farber Cancer Institute
Downloads 42 (1,170,409)

Abstract:

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Positive-selection CRISPR-Cas9 screen, mutant IDH, (R)-2HG, H3K4, histone methylation, oncogenic transformation, epigenetics, cancer metabolism, AML, glioma Introduction: