Harvard University - Dana-Farber Cancer Institute, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Duke University, affiliation not provided to SSRN, University of Utah, Broad Institute, Harvard University - Dana-Farber Cancer Institute, University of California, Los Angeles (UCLA) - Department of Psychiatry and Biobehavioral Sciences, affiliation not provided to SSRN, Duke University, affiliation not provided to SSRN, University of Oulu - Biocenter Oulu and Harvard University - Dana-Farber Cancer Institute