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Keith L. Ligon

Harvard University - Dana-Farber Cancer Institute

SCHOLARLY PAPERS

2

DOWNLOADS

82

TOTAL CITATIONS

0

Scholarly Papers (2)

1.

Title: (R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Tumorigenesis in IDH-Mutant Cancers

Number of pages: 65 Posted: 22 Dec 2021
Harvard University - Dana-Farber Cancer Institute, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Duke University, affiliation not provided to SSRN, University of Utah, Broad Institute, Harvard University - Dana-Farber Cancer Institute, University of California, Los Angeles (UCLA) - Department of Psychiatry and Biobehavioral Sciences, affiliation not provided to SSRN, Duke University, affiliation not provided to SSRN, University of Oulu - Biocenter Oulu and Harvard University - Dana-Farber Cancer Institute
Downloads 42 (1,170,409)

Abstract:

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Positive-selection CRISPR-Cas9 screen, mutant IDH, (R)-2HG, H3K4, histone methylation, oncogenic transformation, epigenetics, cancer metabolism, AML, glioma Introduction:

2.

2D and 3D Multiplexed Subcellular Profiling of Nuclear Instability in Human Cancer

Number of pages: 40 Posted: 07 Nov 2023
Harvard University - Harvard Medical School, Harvard University - Harvard Medical School, Harvard University - Harvard Medical School, University of Pittsburgh, Harvard University - Harvard Medical School, Harvard University - Harvard Medical School, Harvard University - Harvard Medical School, Harvard University - Harvard Medical School, Harvard University - Dana-Farber Cancer Institute, Harvard University - Harvard Medical School, University of Chicago, Harvard University - Harvard Medical School, Harvard University - Dana-Farber Cancer Institute, Harvard University - Harvard Medical School, Harvard University - Dana-Farber Cancer Institute, Harvard University - Laboratory of Systems Pharmacology, Harvard Medical School - Department of Pathology and Independent
Downloads 40 (1,183,237)

Abstract:

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Glioblastoma, lamins, DNA damage, neoplasms, inflammation, cGAS, STING, immunofluorescence, Pathology, multiplexed imaging, systems biology, computational biology, spatial analysis, spatial correlation, CyCIF, fluorescence microscopy, animal models, molecular pathology