University of Birmingham - Institute of Metabolism and Systems Research, University of Oxford - Hypoxia and Angiogenesis Group, University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham - Institute of Metabolism and Systems Research, University of Tartu - Centre of Excellence for Genomics and Translational Medicine, University of Tartu - Centre of Excellence for Genomics and Translational Medicine, University of Birmingham - University Hospital Birmingham NHS Foundation Trust and Institute of Cancer and Genomic Science, University of Glasgow - Beatson Institute for Cancer Research, University of Tartu - Centre of Excellence for Genomics and Translational Medicine, University of Birmingham - Institute of Metabolism and Systems Research, University of Birmingham - Institute of Metabolism and Systems Research, University of Oxford - Hypoxia and Angiogenesis Group and University of Birmingham - Institute of Metabolism and Systems Research

University of Bristol - Bristol Medical School, Queen Mary University of London - Wolfson Institute of Population Health, affiliation not provided to SSRN, Belfast Health and Social Care Trust, affiliation not provided to SSRN, University Hospitals of Derby and Burton NHS Foundation Trust, Nottingham Breast Institute, affiliation not provided to SSRN, Queen's University Belfast, University of Birmingham - University Hospital Birmingham NHS Foundation Trust and Institute of Cancer and Genomic Science, affiliation not provided to SSRN, University of Leeds - St. James's University Hospital and affiliation not provided to SSRN