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Patrice Vanelle

Aix Marseille Université

SCHOLARLY PAPERS

10

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385

TOTAL CITATIONS

0

Scholarly Papers (10)

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1.

New Potent Ev-A71 Antivirals Targeting Capsid

Number of pages: 41 Posted: 19 Apr 2024
Hugo Roux, Franck Touret, Omar Khoumeri, Chaimae Majdi, Pietro Sciò Pietro Sciò, Romano Silvestri, Patrice Vanelle and Manon Roche
CNRS-IRD-Collège de France UMR 34 CEREGE - Aix-Marseille Université, Aix Marseille Université - Emerging Viruses Unit, CNRS-IRD-Collège de France UMR 34 CEREGE - Aix-Marseille Université, CNRS-IRD-Collège de France UMR 34 CEREGE - Aix-Marseille Université, Sapienza University of Rome, Sapienza University of Rome - Department of Chemistry and Drug Technologies, Aix Marseille Université and CNRS-IRD-Collège de France UMR 34 CEREGE - Aix-Marseille Université
Downloads 69 (883,195)

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EV-A71, Capsid binder, Structure-based design, Structure-activity relationships, Heterocyclic compounds

2.

Hit-to-Lead Optimization of 4,5-Dihydrofuran-3-Sulfonyl Scaffold Against Leishmania Amazonensis. Effect of an Aliphatic Moiety

Number of pages: 22 Posted: 24 Jul 2024
Patrice Vanelle, Oscar Leonardo Avendano Leon, Fabiana Maia Santos Urbancg Moncorvo, Christophe Curti, Youssef Kabri, Redon Sébastien and Eduardo Caio Torres-Santos
Aix Marseille Université, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Aix-Marseille University and Oswaldo Cruz Foundation (FIOCRUZ) - Oswaldo Cruz Institute
Downloads 63 (933,592)

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Leishmaniasis, pharmacomodulation, 4, 5-dihydrofuran, amidoxime, manganese (III) acetate

3.

New Antiplasmodial 4-Amino-Thieno[3,2-D]Pyrimidines with Improved Intestinal Permeability and Microsomal Stability

Downloads 58 (980,173)

New Antiplasmodial 4-Amino-Thieno[3,2-D]Pyrimidines with Improved Intestinal Permeability and Microsomal Stability

Number of pages: 30 Posted: 17 Sep 2022
Prisca Lagardère, Romain Mustière, Nadia Amanzougaghene, Sébastien Hutter, Marion Casanova, Jean-François Franetich, Shahin Tajeri, Aurélie Malzert-Fréon, Sophie Corvaisier, Nadine Azas, Patrice Vanelle, Pierre Verhaeghe, Nicolas Primas, Dominique Mazier, Nicolas Masurier and Vincent Lisowski
University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM), Aix Marseille Université, Sorbonne University, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille University, Sorbonne University, Sorbonne University, Normandie Université, Normandie Université, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille Université, UNIMES - Université de Nîmes - CHU de Nîmes (Centre Hospitalier Universitaire de Nîmes), Aix Marseille Université, Sorbonne University, University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM) and University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM)
Downloads 33 (1,311,254)

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malaria, thienopyrimidine, erythocytic, hepatic, Plasmodium, solubility, permeability

New Antiplasmodial 4-Amino-Thieno[3,2-d]Pyrimidines with Improved Intestinal Permeability and Microsomal Stability

Number of pages: 30 Posted: 17 Sep 2022
Prisca Lagardère, Romain Mustière, Nadia Amanzougaghene, Sébastien Hutter, Marion Casanova, Jean-François Franetich, Shahin Tajeri, Aurélie Malzert-Fréon, Sophie Corvaisier, Nadine Azas, Patrice Vanelle, Pierre Verhaeghe, Nicolas Primas, Dominique Mazier, Nicolas Masurier and Vincent Lisowski
University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM), Aix Marseille Université, Sorbonne University, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille University, Sorbonne University, Sorbonne University, Normandie Université, Normandie Université, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille Université, UNIMES - Université de Nîmes - CHU de Nîmes (Centre Hospitalier Universitaire de Nîmes), Aix Marseille Université, Sorbonne University, University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM) and University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM)
Downloads 25 (1,430,393)

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malaria, thienopyrimidine, erythocytic, hepatic, Plasmodium, solubility, permeability

4.

Design and Synthesis of Novel Thioether Analogs as Promising Antiviral Agents: In Vitro Activity Against Enteroviruses of Interest

Number of pages: 66 Posted: 14 Jan 2025
Hugo Roux, Franck Touret, Pietro Sciò Pietro Sciò, Hawa Sophia Bouzidi, Carole Di Giorgio, Florence Gattacceca, Omar Khoumeri, Romano Silvestri, Patrice Vanelle and Manon Roche
CNRS-IRD-Collège de France UMR 34 CEREGE - Aix-Marseille Université, Aix Marseille Université - Emerging Viruses Unit, Sapienza University of Rome, CNRS-IRD-Collège de France UMR 34 CEREGE - Aix-Marseille Université, Aix Marseille Université, CNRS-IRD-Collège de France UMR 34 CEREGE - Aix-Marseille Université, CNRS-IRD-Collège de France UMR 34 CEREGE - Aix-Marseille Université, Sapienza University of Rome - Department of Chemistry and Drug Technologies, Aix Marseille Université and CNRS-IRD-Collège de France UMR 34 CEREGE - Aix-Marseille Université
Downloads 44 (1,145,425)

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Enterovirus, Capsid binder, Broad-spectrum, Structure-activity relationships, Fused bicycles, heterocyclic compounds

5.

Synthesis of Antiplasmodial 2-Aminothieno[3,2-D]Pyrimidin-4(3h)-One Analogues Using the Scaffold Hopping Strategy

Number of pages: 30 Posted: 17 Jun 2022
Romain Mustière, Prisca Lagardère, Sébastien Hutter, Viviana Dell'Orco, Nadia Amanzougaghene, Shahin Tajeri, Jean-François Franetich, Sophie Corvaisier, Marc Since, Aurélie Malzert-Fréon, Nicolas Masurier, Vincent Lisowski, Pierre Verhaeghe, Dominique Mazier, Nadine Azas, Patrice Vanelle and Nicolas Primas
Aix Marseille Université, University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM), Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille Université, Sorbonne University, Sorbonne University, Sorbonne University, Normandie Université, Normandie Université, Normandie Université, University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM), University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM), UNIMES - Université de Nîmes - CHU de Nîmes (Centre Hospitalier Universitaire de Nîmes), Sorbonne University, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille Université and Aix Marseille Université
Downloads 40 (1,183,237)

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Malaria, Plasmodium, scaffold hopping, thienopyrimidinone

6.

Novel Thienopyrimidones Targeting Hepatic and Erythrocytic Stages of Plasmodium Parasites with Increased Microsomal Stability

Number of pages: 33 Posted: 20 Jul 2023
Prisca Lagardère, Romain Mustière, Nadia Amanzougaghene, Sébastien Hutter, Marion Casanova, Jean-François Franetich, Shahin Tajeri, Aurélie Malzert-Fréon, Sophie Corvaisier, Marc Since, Nadine Azas, Patrice Vanelle, Pierre Verhaeghe, Nicolas Primas, Dominique Mazier, Nicolas Masurier and Vincent Lisowski
University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM), Aix Marseille Université, Sorbonne University, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille University, Sorbonne University, Sorbonne University, Normandie Université, Normandie Université, Normandie Université, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille Université, University Grenoble Alpes, Aix Marseille Université, Sorbonne University, University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM) and University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM)
Downloads 31 (1,304,549)

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Malaria, Thienopyrimidine, Erythocytic, Hepatic, Plasmodium, Microsomal Stability, Permeability

7.

Mild Synthesis of Benzo[D]Thiazoles and Chalcogenol Esters Through Reduction of Disulfides and Diselenides Promoted by Enamine-Based Organic Electron Donors

Number of pages: 6 Posted: 25 Mar 2025
Anne Roly Obah Kosso, Julie Broggi, Patrice Vanelle and Redon Sébastien
affiliation not provided to SSRN, CNRS-IRD-Collège de France UMR 34 CEREGE - Aix-Marseille Université, Aix Marseille Université and Aix-Marseille University
Downloads 22 (1,424,331)

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Organic Electron DonorsTDAEDisulfide bondsDiselenide bondsBenzothiazoles

8.

Towards novel thiazolidine-2,4-diones. Synthesis, anticancer activity, DFT, and molecular docking

Number of pages: 33 Posted: 30 Apr 2026
Hussein El-Kashef, Ilaria Lampronti, Omar Khoumeri, Redon Sébastien, Ahmed Mohamed, Al-Ahmady Ezzat, Chiara Tupini, Nadine maria Barbieri, Patrice Vanelle and Nicolas Primas
Assiut University, affiliation not provided to SSRN, CNRS-IRD-Collège de France UMR 34 CEREGE - Aix-Marseille Université, Aix-Marseille University, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Aix Marseille Université and Aix Marseille Université
Downloads 20 (1,470,786)

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Keywords: Thiazolidinediones, thiazolidine-2, 4-diones, Curtius rearrangement, anti-breast cancer, DFT, molecular docking.

9.

Discovery of antileishmanial hits in the 3-nitroimidazo[1,2-a]pyridine series via newly optimized TDAE methodology at position 2

Number of pages: 34 Posted: 15 Oct 2025
Inès Jacquet, Romain Paoli-Lombardo, Caroline Castera-Ducros, Hugo Pomares, Sandra Bourgeade-Delmas, Patrice Vanelle and Nicolas Primas
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Aix Marseille Université and Aix Marseille Université
Downloads 20 (1,448,301)

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3-Nitroimidazo[1, 2-a]pyridine, TDAE, N-Tosylbenzylimine, Leishmania, Nitroaromatic compounds, Nucleophilic aromatic substitution, Palladium-catalyzed cross-coupling

10.

Novel hybrid 1,4-naphthoquinone-endoperoxide antimalarial hits: synthesis, stereoisomeric separation, and biological evaluation

Number of pages: 44 Posted: 27 Mar 2026
Alexandre Benech, Sébastien Hutter, Nicolas Vanthuyne, Omar Khoumeri, Christophe Curti, Patrice Vanelle, Thierry Terme and Nadine Azas
affiliation not provided to SSRN, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille Université - iSm2, CNRS-IRD-Collège de France UMR 34 CEREGE - Aix-Marseille Université, affiliation not provided to SSRN, Aix Marseille Université, affiliation not provided to SSRN and Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens
Downloads 18 (1,470,786)

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naphthoquinone, endoperoxide, Mn(acac)3, stereoisomers, Plasmodium falciparum, therapeutic chemistry, Rational drug design