default author photo

Nicolas Primas

Aix Marseille Université

3, avenue Robert Schuman

58 Boulevard Charles Livon

Aix-en-Provence, 13100

France

  • Aix Marseille Université

SCHOLARLY PAPERS

5

DOWNLOADS

169

TOTAL CITATIONS

0

Scholarly Papers (5)

Actions:
Email selected abstracts
1.

New Antiplasmodial 4-Amino-Thieno[3,2-D]Pyrimidines with Improved Intestinal Permeability and Microsomal Stability

Downloads 58 (980,173)

New Antiplasmodial 4-Amino-Thieno[3,2-D]Pyrimidines with Improved Intestinal Permeability and Microsomal Stability

Number of pages: 30 Posted: 17 Sep 2022
Prisca Lagardère, Romain Mustière, Nadia Amanzougaghene, Sébastien Hutter, Marion Casanova, Jean-François Franetich, Shahin Tajeri, Aurélie Malzert-Fréon, Sophie Corvaisier, Nadine Azas, Patrice Vanelle, Pierre Verhaeghe, Nicolas Primas, Dominique Mazier, Nicolas Masurier and Vincent Lisowski
University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM), Aix Marseille Université, Sorbonne University, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille University, Sorbonne University, Sorbonne University, Normandie Université, Normandie Université, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille Université, UNIMES - Université de Nîmes - CHU de Nîmes (Centre Hospitalier Universitaire de Nîmes), Aix Marseille Université, Sorbonne University, University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM) and University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM)
Downloads 33 (1,311,254)

Abstract:

Loading...

malaria, thienopyrimidine, erythocytic, hepatic, Plasmodium, solubility, permeability

New Antiplasmodial 4-Amino-Thieno[3,2-d]Pyrimidines with Improved Intestinal Permeability and Microsomal Stability

Number of pages: 30 Posted: 17 Sep 2022
Prisca Lagardère, Romain Mustière, Nadia Amanzougaghene, Sébastien Hutter, Marion Casanova, Jean-François Franetich, Shahin Tajeri, Aurélie Malzert-Fréon, Sophie Corvaisier, Nadine Azas, Patrice Vanelle, Pierre Verhaeghe, Nicolas Primas, Dominique Mazier, Nicolas Masurier and Vincent Lisowski
University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM), Aix Marseille Université, Sorbonne University, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille University, Sorbonne University, Sorbonne University, Normandie Université, Normandie Université, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille Université, UNIMES - Université de Nîmes - CHU de Nîmes (Centre Hospitalier Universitaire de Nîmes), Aix Marseille Université, Sorbonne University, University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM) and University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM)
Downloads 25 (1,430,393)

Abstract:

Loading...

malaria, thienopyrimidine, erythocytic, hepatic, Plasmodium, solubility, permeability

2.

Synthesis of Antiplasmodial 2-Aminothieno[3,2-D]Pyrimidin-4(3h)-One Analogues Using the Scaffold Hopping Strategy

Number of pages: 30 Posted: 17 Jun 2022
Romain Mustière, Prisca Lagardère, Sébastien Hutter, Viviana Dell'Orco, Nadia Amanzougaghene, Shahin Tajeri, Jean-François Franetich, Sophie Corvaisier, Marc Since, Aurélie Malzert-Fréon, Nicolas Masurier, Vincent Lisowski, Pierre Verhaeghe, Dominique Mazier, Nadine Azas, Patrice Vanelle and Nicolas Primas
Aix Marseille Université, University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM), Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille Université, Sorbonne University, Sorbonne University, Sorbonne University, Normandie Université, Normandie Université, Normandie Université, University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM), University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM), UNIMES - Université de Nîmes - CHU de Nîmes (Centre Hospitalier Universitaire de Nîmes), Sorbonne University, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille Université and Aix Marseille Université
Downloads 40 (1,183,237)

Abstract:

Loading...

Malaria, Plasmodium, scaffold hopping, thienopyrimidinone

3.

Novel Thienopyrimidones Targeting Hepatic and Erythrocytic Stages of Plasmodium Parasites with Increased Microsomal Stability

Number of pages: 33 Posted: 20 Jul 2023
Prisca Lagardère, Romain Mustière, Nadia Amanzougaghene, Sébastien Hutter, Marion Casanova, Jean-François Franetich, Shahin Tajeri, Aurélie Malzert-Fréon, Sophie Corvaisier, Marc Since, Nadine Azas, Patrice Vanelle, Pierre Verhaeghe, Nicolas Primas, Dominique Mazier, Nicolas Masurier and Vincent Lisowski
University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM), Aix Marseille Université, Sorbonne University, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille University, Sorbonne University, Sorbonne University, Normandie Université, Normandie Université, Normandie Université, Aix Marseille University - UMR VITROME - Tropical Eukaryotic Pathogens, Aix Marseille Université, University Grenoble Alpes, Aix Marseille Université, Sorbonne University, University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM) and University of Montpellier - Institut des Biomolécules Max Mousseron (IBMM)
Downloads 31 (1,304,549)

Abstract:

Loading...

Malaria, Thienopyrimidine, Erythocytic, Hepatic, Plasmodium, Microsomal Stability, Permeability

4.

Towards novel thiazolidine-2,4-diones. Synthesis, anticancer activity, DFT, and molecular docking

Number of pages: 33 Posted: 30 Apr 2026
Hussein El-Kashef, Ilaria Lampronti, Omar Khoumeri, Redon Sébastien, Ahmed Mohamed, Al-Ahmady Ezzat, Chiara Tupini, Nadine maria Barbieri, Patrice Vanelle and Nicolas Primas
Assiut University, affiliation not provided to SSRN, CNRS-IRD-Collège de France UMR 34 CEREGE - Aix-Marseille Université, Aix-Marseille University, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Aix Marseille Université and Aix Marseille Université
Downloads 20 (1,470,786)

Abstract:

Loading...

Keywords: Thiazolidinediones, thiazolidine-2, 4-diones, Curtius rearrangement, anti-breast cancer, DFT, molecular docking.

5.

Discovery of antileishmanial hits in the 3-nitroimidazo[1,2-a]pyridine series via newly optimized TDAE methodology at position 2

Number of pages: 34 Posted: 15 Oct 2025
Inès Jacquet, Romain Paoli-Lombardo, Caroline Castera-Ducros, Hugo Pomares, Sandra Bourgeade-Delmas, Patrice Vanelle and Nicolas Primas
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Aix Marseille Université and Aix Marseille Université
Downloads 20 (1,448,301)

Abstract:

Loading...

3-Nitroimidazo[1, 2-a]pyridine, TDAE, N-Tosylbenzylimine, Leishmania, Nitroaromatic compounds, Nucleophilic aromatic substitution, Palladium-catalyzed cross-coupling