IRCSS Sacro Cuore Hospital, - Department of Infectious – Tropical Diseases and Microbiology, Interactive Research and Development Global, Singapore, University of California, San Francisco (UCSF) - UCSF Center for Tuberculosis, Epicentre (Paris), Interactive Research and Development (IRD), Karachi, Pakistan, Interactive Research and Development (IRD), Karachi, Pakistan, Interactive Research and Development (IRD), Karachi, Pakistan, National Scientific Center of Phthisiopulmonology, University of Tübingen - Mycobacteriology Unit, Epicentre (Paris), National Scientific Center of Phthisiopulmonology, Médecins Sans Frontières (London), University of Montpellier - Translational Research in HIV and Infectious Diseases (TransVIHMI), Médecins Sans Frontières, Mumbai, India, Médecins Sans Frontières, Geneva, Switzerland, City Center of Phthisiopulmonology, Institute of Tropical Medicine - Mycobacteriology Unit, Hanoi Medical University - Vietnam National Lung Hospital, Médecins Sans Frontières, Geneva, Switzerland, Research Center Borstel, Partners In Health Lesotho, Médecins Sans Frontières, Harvard University - Department of Global Health and Social Medicine, University of Cape Town (UCT) - Division of Clinical Pharmacology, Socios En Salud Sucursal Peru, Institute of Tropical Medicine - Mycobacteriology Unit, The Indus Hospital and Health Network, University of California, San Francisco (UCSF) - UCSF Center for Tuberculosis, Hanoi Lung Hospital, Hanoi Medical University - Vietnam National Tuberculosis Programme, Partners In Health Lesotho, University College London - MRC Clinical Trials Unit, Indian Council of Medical Research (ICMR), Indian Council of Medical Research (ICMR) - National AIDS Research Institute, Hanoi Lung Hospital, Pham Ngoc Thach Hospital, University of California, San Francisco (UCSF) - UCSF Center for Tuberculosis, University of California, San Francisco (UCSF) - UCSF Center for Tuberculosis, Socios En Salud Sucursal Peru, University of Tübingen - Mycobacteriology Unit, The Indus Hospital and Health Network, Hospital Nacional Sergio E. Bernales, Harvard University - Division of Global Health Equity, Partners In Health Lesotho, Hospital Nacional Hipólito Unanue, Lima, Harvard University - Division of Global Health Equity, Médecins sans Frontières (Paris), Harvard University - Department of Global Health and Social Medicine and Independent

University of Montpellier - MIVEGEC, Centre Pasteur du Cameroun (CPC), University of Montpellier, Lusaka University Teaching Hospital, Epicentre (Mbarara), Foundation for Innovative New Diagnostics, the global alliance for diagnostics - FIND, KNCV Tuberculosis Foundation, KNCV Tuberculosis Foundation, Makerere University - Johns Hopkins University Research Collaboration, The University of Western Australia - Division of Infection and Immunity, Centre Pasteur of Cameroon, MU-JHU Care Ltd - MUJHU Research Collaboration, Epicentre (Mbarara), Lusaka University Teaching Hospital, University of Bordeaux, University of Montpellier - Translational Research in HIV and Infectious Diseases (TransVIHMI) and Independent

Epicentre (Paris), Epicentre (Mbarara), Epicentre (Mbarara), Médecins sans Frontières, Homabay, Kenya, Médecins sans Frontières, Maputo, Mozambique, Médecins sans Frontières, Eshowe, South Africa, Mbarara Regional Referral Hospital, Epicentre (Mbarara), Médecins sans Frontières, Eshowe, South Africa, Epicentre (Paris), Médecins sans Frontières, Eshowe, South Africa, Médecins Sans Frontières - Southern Africa Medical Unit, Médecins sans Frontières (Paris), Uganda Tuberculosis Implementation Research Consortium, Government of Kenya - Kenya Ministry of Health, Government of Kenya, Kenya Ministry of Health, National Tuberculosis, Leprosy and Lung Disease Programme, Department of Health, KwaZulu-Natal Province, Department of Health, King Cetswayo District, Republic of Mozambique - Ministry of Health, Médecins sans Frontières, Nairobi, Kenya, Médecins sans Frontières, Nairobi, Kenya, Epicentre (Mbarara), Epicentre (Paris), University of Tübingen - Mycobacteriology Unit, Elizabeth Glaser Pediatric AIDS Foundation (Switzerland) - Department of Innovation and New Technology, Médecins Sans Frontières - Southern Africa Medical Unit, Makerere University, University College London - Institute for Global Health and University of Montpellier - Translational Research in HIV and Infectious Diseases (TransVIHMI)

MU-JHU Care Ltd - MUJHU Research Collaboration, MU-JHU Care Ltd - MUJHU Research Collaboration, University of Bordeaux - National Institute for Health and Medical Research (INSERM) UMR 1219, Chantal Biya Foundation - Mother and Child Center, Universite Félix Houphouet Boigny - University of Felix Houphouet Boigny - Teaching Unit of Dermatology and Infectiology, Solthis (France), Instituto Nacional de Saúde., Institute Pasteur du Cambodge - Epidemiology and Public Health Unit, Epicentre (Mbarara), Ola During Children’s Hospital, University of Montpellier - Translational Research in HIV and Infectious Diseases (TransVIHMI), University Hospital of Treichville - PACCI ANRS Research Programme, SOLTHIS, Epicentre (Mbarara), Institute Pasteur du Cambodge - Epidemiology and Public Health Unit, Institute Pasteur du Cambodge - Epidemiology and Public Health Unit, Instituto Nacional de Saúde., University of Bordeaux - National Institute for Health and Medical Research (INSERM) UMR 1219, University of Bordeaux - National Institute for Health and Medical Research (INSERM) UMR 1219, University of Montpellier - MIVEGEC, Centre Pasteur du Cameroun (CPC), University of Bordeaux - National Institute for Health and Medical Research (INSERM) UMR 1219, Soutien Pneumologique International, Soutien Pneumologique International, Uganda Tuberculosis Implementation Research Consortium, Ministry of Health and Sanitation (Sierra Leone), Côte d’Ivoire NTP, Cameroon National Tuberculosis Program, affiliation not provided to SSRNMozambique National Tuberculosis Programme (NTP), Sierra Leone National Tuberculosis Program, UNICEF USA, World Health Organization (WHO) - World Health Organization, Geneva, Royal Government of Cambodia - National Center for Tuberculosis and Leprosy Control (CENAT), University of Bordeaux - National Institute for Health and Medical Research (INSERM) UMR 1219, University of Montpellier - Translational Research in HIV and Infectious Diseases (TransVIHMI), University of Bordeaux - National Institute for Health and Medical Research (INSERM) UMR 1219 and Independent

University of Bordeaux, University of Bordeaux, University of Bordeaux, Institut Pasteur du Cambodge, Epidemiology & Public Health Unit, University of Cape Town (UCT) - Division of Clinical Pharmacology, University of North Carolina (UNC) at Chapel Hill - National Institute of Health, Chantal Biya Foundation - Mother and Child Center, Universite Félix Houphouet Boigny - University of Felix Houphouet Boigny - Teaching Unit of Dermatology and Infectiology, Epicentre (Mbarara), affiliation not provided to SSRN, University of Zambia (UNZA), Eduardo Mondlane University (UEM) - Maputo Central Hospital, Eduardo Mondlane University (UEM) - Maputo Central Hospital, affiliation not provided to SSRN, Makerere University - Johns Hopkins University Research Collaboration, University of Zambia (UNZA), University of Zambia (UNZA), Institute Pasteur du Cambodge - Epidemiology and Public Health Unit, Institute Pasteur du Cambodge - Epidemiology and Public Health Unit, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University Hospital of Treichville - PACCI ANRS Research Programme, affiliation not provided to SSRN, Makerere University, Epicentre (Mbarara), Instituto Nacional de Saúde., affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Nairobi, Imperial College London, Royal Government of Cambodia - National Center for Tuberculosis and Leprosy Control (CENAT), University of Melbourne, affiliation not provided to SSRN, MU-JHU Care Ltd - MUJHU Research Collaboration, University of Montpellier - Translational Research in HIV and Infectious Diseases (TransVIHMI) and Independent