University of Oxford, Imperial College London, Tel Aviv University, Imperial College London - Section of Paediatric Infectious Disease, Imperial College London, Imperial College London, Imperial College London, University of Cambridge, Government of the United Kingdom - Barts Health NHS Trust, Wellcome Sanger Institute, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), Imperial College London - Section of Paediatric Infectious Disease, Imperial College London - Section of Paediatric Infectious Disease, St Mary’s Hospital, Great Ormond Street Hospital for Children NHS Foundation Trust - Paediatric Intensive Care Unit and Great Ormond Street Hospital for Children NHS Foundation Trust