affiliation not provided to SSRN, Rutgers, The State University of New Jersey - Research Collaboratory for Structural Bioinformatics Protein Data Bank, affiliation not provided to SSRN, University of Southern California, Rutgers, The State University of New Jersey - Research Collaboratory for Structural Bioinformatics Protein Data Bank, University of Southern California, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Technische Universität Berlin (TU Berlin) - Chair of Bioanalytics, Rutgers, The State University of New Jersey - Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey - Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey - Research Collaboratory for Structural Bioinformatics Protein Data Bank, Tata Institute of Fundamental Research (TIFR), Tata Institute of Fundamental Research (TIFR), University of Southern California, University of Connecticut - Department of Molecular Biology and Biophysics, The University of Osaka, European Bioinformatics Institute, European Bioinformatics Institute, Rutgers, The State University of New Jersey - Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey - Research Collaboratory for Structural Bioinformatics Protein Data Bank and UC, San Francisco - Dept. of Biopharmaceutical Sciences and Pharmaceutical Chemistry