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Leen Rigouts

Institute of Tropical Medicine - Mycobacteriology Unit

B-2000 Antwerp

Belgium

SCHOLARLY PAPERS

5

DOWNLOADS

495

TOTAL CITATIONS

1

Scholarly Papers (5)

1.

Frameshift Mutations in Rv0678 Preserve Bedaquiline Susceptibility in Mycobacterium Tuberculosis by Maintaining Protein Integrity

Number of pages: 15 Posted: 26 Mar 2024
University of Tübingen - Institute of Tropical Medicine, Nottingham Trent University, Institute of Tropical Medicine - Mycobacteriology Unit, Institute of Tropical Medicine - Mycobacteriology Unit, affiliation not provided to SSRN, Institute of Tropical Medicine - Mycobacteriology Unit, University of Antwerp - Centre for Population, Family, and Health and Institute of Tropical Medicine - Mycobacteriology Unit
Downloads 199 (382,358)
Citation 1

Abstract:

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drug-resistant tuberculosis, bedaquiline, resistance

2.

High Rates of False Rifampicin Resistance in Paucibacillary Tuberculosis Patients by Xpert MTB/RIF Ultra

Number of pages: 19 Posted: 13 Aug 2024
University of Tübingen - Institute of Tropical Medicine, Rwanda Biomedical Centre, Government of the Republic of the Sudan - Integrated Vector Management Department, Rwanda Biomedical Centre, Rwanda Biomedical Centre, University of Tübingen - Institute of Tropical Medicine, University of Tübingen - Institute of Tropical Medicine, Institute of Tropical Medicine - Mycobacteriology Unit, Institute of Tropical Medicine, Institute of Tropical Medicine - Department of Clinical Sciences, Rwanda Biomedical Center, Rwanda Biomedical Center - Tuberculosis and Other Respiratory Diseases Division, Rwanda Biomedical Center (RBC) - National Reference Laboratory Division, Institute of Tropical Medicine - Mycobacteriology Unit, Institute of Tropical Medicine - Mycobacteriology Unit and Rwanda Biomedical Center (RBC) - National Reference Laboratory Division
Downloads 147 (502,974)

Abstract:

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Positive Predictive Value (PPV), Specifity test, Xpert MTB/RIF Ultra, False-positive, Paucibacillary TB, TB case management

3.

Rifampicin-Resistant Tuberculosis Control in Rwanda Overcomes a Successful Clone That Causes Most Disease Over a Quarter Century

Number of pages: 16 Posted: 02 Mar 2021
Rwanda Biomedical Center (RBC) - National Reference Laboratory Division, Institute of Tropical Medicine - Mycobacteriology Unit, Institute of Tropical Medicine - Mycobacteriology Unit, Institute of Tropical Medicine - Department of Clinical Sciences, Rwanda Biomedical Center (RBC) - National Reference Laboratory Division, Institute of Tropical Medicine - Mycobacteriology Unit, Rwanda Biomedical Center (RBC) - National Reference Laboratory Division, Rwanda Biomedical Center - Tuberculosis and Other Respiratory Diseases Division, University Hospitals Leuven - Clinical Department of Laboratory Medicine and National Reference Center for Respiratory Pathogens, Rwanda Biomedical Center (RBC) - National Reference Laboratory Division, Institute of Tropical Medicine - Mycobacteriology Unit, Rwanda Biomedical Center (RBC) - National Reference Laboratory Division, Institute of Tropical Medicine - Mycobacteriology Unit, Rwanda Biomedical Center (RBC) - National Reference Laboratory Division, Institute of Tropical Medicine - Mycobacteriology Unit, Rwanda Biomedical Center (RBC) - National Reference Laboratory Division, Rwanda Biomedical Center - Tuberculosis and Other Respiratory Diseases Division, University Hospitals Leuven - Clinical Department of Laboratory Medicine and National Reference Center for Respiratory Pathogens, Rwanda Biomedical Center (RBC) - Department of Biomedical Services, Laboratoire de Référence des Mycobactéries, Management Sciences for Health, Rwanda Biomedical Center (RBC) - Medical Research Center (MRC), Institute of Tropical Medicine - Mycobacteriology Unit, Rwanda Biomedical Center - Tuberculosis and Other Respiratory Diseases Division, Institute of Tropical Medicine - Mycobacteriology Unit and Institute of Tropical Medicine - Mycobacteriology Unit
Downloads 78 (816,709)

Abstract:

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4.

Whole Genome Sequencing Precision Medicine Strategy to Shorten Treatment for Rifampicin Resistant Tuberculosis (SMARTT): A Pragmatic, Randomized, Single-Blinded Phase IV Medical Device Trial

Number of pages: 21 Posted: 31 Oct 2025
University of Antwerp - Centre for Population, Family, and Health, Stellenbosch University, Aurum Institute, Stellenbosch University, Stellenbosch University, Aurum Institute, Aurum Institute, Aurum Institute, Aurum Institute, Aurum Institute, Aurum Institute, University of Antwerp, University of Antwerp, University of Antwerp, University of Antwerp, University of Antwerp - Centre for Population, Family, and Health, Institute of Tropical Medicine - Mycobacteriology Unit, University of the Free State, University of the Free State, University of the Free State, University of the Witwatersrand - Faculty of Health Sciences, University of Cape Town (UCT) - Division of Clinical Pharmacology, University of the Free State, Walter Sisulu University - Department of Medicine, University of the Free State, Interuniversity Institute for Biostatistics and statistical Bioinformatics (IBioStat) - Data Science Institute, Aurum Institute, Stellenbosch University - Division of Molecular Biology and Human Genetics and Aurum Institute for Health Research
Downloads 71 (867,774)

Abstract:

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tuberculosis, drug resistance, randomised clinical trial, pragmatic trial, whole genome sequencing, precision medicine

5.

High Frequency of Bedaquiline Resistance in Programmatically Treated Drug-Resistant TB Patients with Sustained Culture-Positivity in Cape Town, South Africa

Posted: 30 Sep 2022
Stellenbosch University - Division of Molecular Biology and Human Genetics, University of Antwerp - Centre for Population, Family, and Health, Stellenbosch University - Division of Molecular Biology and Human Genetics, Natera, Inc., Stellenbosch University - Division of Molecular Biology and Human Genetics, Stellenbosch University - Division of Molecular Biology and Human Genetics, University of California, San Francisco (UCSF) - Division of Pulmonary and Critical Care Medicine, Stellenbosch University - Division of Molecular Biology and Human Genetics, National Health Laboratory Services (NHLS), Stellenbosch University - Division of Molecular Biology and Human Genetics, Médecins sans Frontières, Eshowe, South Africa, The Translational Genomics Research Institute (TGen), The Translational Genomics Research Institute (TGen), University of Antwerp - Centre for Population, Family, and Health, University of Basel - Swiss Tropical and Public Health Institute, Institute of Tropical Medicine - Mycobacteriology Unit, Brooklyn Chest Hospital, University of Cape Town (UCT) - Centre for Lung Infection and Immunity, Médecins sans Frontières, Eshowe, South Africa, Stellenbosch University - Division of Molecular Biology and Human Genetics, University of California, San Francisco (UCSF) - Division of Pulmonary and Critical Care Medicine, University of Cape Town (UCT) - Division of Medical Microbiology and Stellenbosch University - DST/NRF Centre of Excellence for Biomedical Tuberculosis Research

Abstract:

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Tuberculosis, drug-resistant tuberculosis, bedaquiline, novel drug, programmatic, bedaquiline-resistance, bedaquiline phenotypic DST, whole genome sequencing, targeted deep sequencing