default author photo

Anzaan Dippenaar

University of Antwerp - Centre for Population, Family, and Health

SCHOLARLY PAPERS

5

DOWNLOADS

255

TOTAL CITATIONS

0

Scholarly Papers (5)

1.

Whole Genome Sequencing Precision Medicine Strategy to Shorten Treatment for Rifampicin Resistant Tuberculosis (SMARTT): A Pragmatic, Randomized, Single-Blinded Phase IV Medical Device Trial

Number of pages: 21 Posted: 31 Oct 2025
University of Antwerp - Centre for Population, Family, and Health, Stellenbosch University, Aurum Institute, Stellenbosch University, Stellenbosch University, Aurum Institute, Aurum Institute, Aurum Institute, Aurum Institute, Aurum Institute, Aurum Institute, University of Antwerp, University of Antwerp, University of Antwerp, University of Antwerp, University of Antwerp - Centre for Population, Family, and Health, Institute of Tropical Medicine - Mycobacteriology Unit, University of the Free State, University of the Free State, University of the Free State, University of the Witwatersrand - Faculty of Health Sciences, University of Cape Town (UCT) - Division of Clinical Pharmacology, University of the Free State, Walter Sisulu University - Department of Medicine, University of the Free State, Interuniversity Institute for Biostatistics and statistical Bioinformatics (IBioStat) - Data Science Institute, Aurum Institute, Stellenbosch University - Division of Molecular Biology and Human Genetics and Aurum Institute for Health Research
Downloads 84 (867,774)

Abstract:

Loading...

tuberculosis, drug resistance, randomised clinical trial, pragmatic trial, whole genome sequencing, precision medicine

2.

The DREstimator - Automated Interpretation of Variants in Candidate Resistance Genes in Mycobacterium Tuberculosis to Move Whole Genome Sequencing Towards Clinical Actionability

Number of pages: 16 Posted: 07 Nov 2025
University of Antwerp, University of Antwerp, University of Antwerp, University of Antwerp, University of Antwerp, University of Antwerp - Centre for Population, Family, and Health, University of Antwerp and University of Antwerp - Centre for Population, Family, and Health
Downloads 72 (875,328)

Abstract:

Loading...

tuberculosis, antimicrobial resistance, genomics, next generation sequencing, whole genome sequencing, variant interpretation

3.

Discovery and Biological Evaluation of an Adamantyl-Amide Derivative with Likely MmpL3 Inhibitory Activity

Number of pages: 23 Posted: 02 Dec 2022
University of the Western Cape, Stellenbosch University, Stellenbosch University - Division of Molecular Biology and Human Genetics, University of Antwerp - Centre for Population, Family, and Health, University of the Western Cape, University of Cape Town (UCT) - SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, University of Cape Town (UCT) - SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, University of the Western Cape, World Health Organization (WHO) - INN Programme and Classification of Medical Products and Stellenbosch University
Downloads 59 (989,921)

Abstract:

Loading...

Mycobacterium tuberculosis, MmpL3, anti-mycobacterial, screening, whole genome sequencing

4.

Economic Evaluation of Whole Genome Sequencing Guided Treatment for Rifampicin-Resistant Tuberculosis: A Within-Trial Analysis of the SMARTT Trial

Number of pages: 18 Posted: 18 Apr 2026
University of Antwerp, University of Antwerp - Centre for Health Economics Research and Modelling Infectious Diseases (CHERMID), Aurum Institute, Stellenbosch University, Aurum Institute, Stellenbosch University - Division of Molecular Biology and Human Genetics, Ghent University, Interuniversity Institute for Biostatistics and statistical Bioinformatics (IBioStat) - Data Science Institute, Africa Health Research Institute, University of Antwerp, University of Antwerp - Centre for Population, Family, and Health, University of the Free State, University of Antwerp, University of the Free State, University of Antwerp, University of the Free State, Aurum Institute, Aurum Institute, Aurum Institute, University of Antwerp, Stellenbosch University, Aurum Institute for Health Research and University of Antwerp - Centre for Population, Family, and Health
Downloads 40 (1,263,436)

Abstract:

Loading...

tuberculosis, drug-resistance, whole genome sequencing, health economics, cost-effectiveness, within-trial analysis, DALY, ICER, INMB, ROI

5.

High Frequency of Bedaquiline Resistance in Programmatically Treated Drug-Resistant TB Patients with Sustained Culture-Positivity in Cape Town, South Africa

Posted: 30 Sep 2022
Stellenbosch University - Division of Molecular Biology and Human Genetics, University of Antwerp - Centre for Population, Family, and Health, Stellenbosch University - Division of Molecular Biology and Human Genetics, Natera, Inc., Stellenbosch University - Division of Molecular Biology and Human Genetics, Stellenbosch University - Division of Molecular Biology and Human Genetics, University of California, San Francisco (UCSF) - Division of Pulmonary and Critical Care Medicine, Stellenbosch University - Division of Molecular Biology and Human Genetics, National Health Laboratory Services (NHLS), Stellenbosch University - Division of Molecular Biology and Human Genetics, Médecins sans Frontières, Eshowe, South Africa, The Translational Genomics Research Institute (TGen), The Translational Genomics Research Institute (TGen), University of Antwerp - Centre for Population, Family, and Health, University of Basel - Swiss Tropical and Public Health Institute, Institute of Tropical Medicine - Mycobacteriology Unit, Brooklyn Chest Hospital, University of Cape Town (UCT) - Centre for Lung Infection and Immunity, Médecins sans Frontières, Eshowe, South Africa, Stellenbosch University - Division of Molecular Biology and Human Genetics, University of California, San Francisco (UCSF) - Division of Pulmonary and Critical Care Medicine, University of Cape Town (UCT) - Division of Medical Microbiology and Stellenbosch University - DST/NRF Centre of Excellence for Biomedical Tuberculosis Research

Abstract:

Loading...

Tuberculosis, drug-resistant tuberculosis, bedaquiline, novel drug, programmatic, bedaquiline-resistance, bedaquiline phenotypic DST, whole genome sequencing, targeted deep sequencing