affiliation not provided to SSRN, University of Pardubice, University Hospital Hradec Kralove, University Hospital Hradec Kralove, Charles University, University Hospital Hradec Kralove, University Hospital Hradec Kralove, University Hospital Hradec Kralove, affiliation not provided to SSRN, University Hospital Hradec Kralove, University of Pardubice, University of Pardubice, University Hospital Hradec Kralove, affiliation not provided to SSRN, affiliation not provided to SSRN, Academy of Sciences of the Czech Republic, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Medical University of Gdansk, Medical University of Gdansk, University Hospital Hradec Kralove, Charles University, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN and University Hospital Hradec Kralove