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Jan Marek

University Hospital Hradec Kralove

SCHOLARLY PAPERS

5

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195

TOTAL CITATIONS

0

Scholarly Papers (5)

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1.

Novel Antitubercular Agents Based on 2,4-Disubstituted 5-(Aryl-2-Ylmethyl)-5h-Pyrrolo[3,2-D]Pyrimidines

Number of pages: 74 Posted: 19 Jun 2025
Vladimir Finger, Martin Vrbicky, Lubica Muckova, Lukas Prchal, Martin Novák, Jan Marek, Ondrej Soukup, Michaela Hympanova, Ales Sorf, Marketa Benkova, Jan Bartacek, Pavel Drabina, Martin Kufa, Ondrej Kovar, Lenka Fikejzlová, Martin Hruby, Oksana Ozhelevska, Johannes Jagob, Jana Zdarova Karasova, Jitka Odvarkova, Iveta Kaderavková, Tomas Rozsypal, Katarzyna Ewa Greber, Krzesimir Ciura, Jiri Janousek, Martin Kratky, Ivone C. Igreja Sa, Pavel Bostik, Radek Sleha, Jaroslav Roh and Jan Korabecny
affiliation not provided to SSRN, University of Pardubice, University Hospital Hradec Kralove, University Hospital Hradec Kralove, Charles University, University Hospital Hradec Kralove, University Hospital Hradec Kralove, University Hospital Hradec Kralove, affiliation not provided to SSRN, University Hospital Hradec Kralove, University of Pardubice, University of Pardubice, University Hospital Hradec Kralove, affiliation not provided to SSRN, affiliation not provided to SSRN, Academy of Sciences of the Czech Republic, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Medical University of Gdansk, Medical University of Gdansk, University Hospital Hradec Kralove, Charles University, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN and University Hospital Hradec Kralove
Downloads 57 (989,921)

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deazapurine, Mycobacterium tuberculosis, pyrrole, pyrimidine, tuberculosis

2.

Rational Design, Synthesis and Evaluation of Piperazine Derivatives as Promising Radioprotective Agents: Toward Next-Generation Alternatives to Amifostine

Number of pages: 35 Posted: 28 Jul 2025
Natálie Živná, Vojtěch Chmil, Alžběta Filipová, Darina Muthná, Martina Řezáčová, Aleš Tichý, Radim Havelek, Marcela Milanová, Lukas Prchal, Rafael Dolezal, Vít Řeháček and Jan Marek
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University Hospital Hradec Kralove, University Hospital Hradec Kralove, University Hospital Hradec Kralove and University Hospital Hradec Kralove
Downloads 37 (1,236,159)

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Radioprotection, Drug design, radiation, radiation medical countermeasures, piperazine, in vitro

3.

2,6-Disubstituted 7-(Naphthalen-2-Ylmethyl)-7h-Purines as a New Class of Potent Antitubercular Agents Inhibiting Dpre1

Number of pages: 85 Posted: 18 May 2023
Vladimir Finger, Tomas Kucera, Radka Kafkova, Lubica Muckova, Rafael Dolezal, Jan Kubes, Martin Novák, Lukas Prchal, Levente Lakatos, Martin Andrs, Michaela Hympanova, Jan Marek, Martin Kufa, Vojtech Spiwok, Ondrej Soukup, Eva Mezeiova, Jiri Janousek, Lenka Nevosadova, Marketa Benkova, Russell Kitson, Martin Kratky, Szilvia Bősze, Katarína Mikušová, Ruben Hartkoorn, Jaroslav Roh and Jan Korabecny
University Hospital Hradec Kralove, University of Defence in Brno, Comenius University, University Hospital Hradec Kralove, University Hospital Hradec Kralove, Charles University, Charles University, University Hospital Hradec Kralove, Eötvös Loránd University, University Hospital Hradec Kralove, University Hospital Hradec Kralove, University Hospital Hradec Kralove, University Hospital Hradec Kralove, University of Chemistry and Technology, Prague, University Hospital Hradec Kralove, University Hospital Hradec Kralove, University Hospital Hradec Kralove, Charles University, University Hospital Hradec Kralove, Charles University, Charles University, Eötvös Loránd University, Comenius University, University of Lille - CHU Lille, Charles University and University Hospital Hradec Kralove
Downloads 37 (1,249,711)

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Tuberculosis, purine, Mycobacterium tuberculosis, DprE1, Structure-activity relationships

4.

Ph-Induced Morphological Reversible Transition from Microparticles to Vesicles for Effective Bacteria Entrapment

Number of pages: 22 Posted: 27 Aug 2024
Vladimir Sincari, Svetlana Lukáš Petrova, Eliézer Jäger, Alessandro Jäger, Rafał Konefał, Veronika Gajdošová, Miroslav Slouf, Michaela Hympanova, Jan Marek, Ondrej Soukup and Martin Hruby
Czech Academy of Sciences, Academy of Sciences of the Czech Republic, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Czech Academy of Sciences, University Hospital Hradec Kralove, University Hospital Hradec Kralove, University Hospital Hradec Kralove and Academy of Sciences of the Czech Republic
Downloads 33 (1,277,121)

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microparticles, pH-responsive, bacteria, microfluidics, vesicles, polymersomes

5.

Ph-Induce Morphological Reversible Transition from Microparticles to Vesicles for Effective Bacteria Entrapment

Number of pages: 18 Posted: 26 Apr 2024
Vladimir Sincari, Svetlana Lukáš Petrova, Eliézer Jäger, Alessandro Jäger, Veronika Gajdošová, Miroslav Slouf, Michaela Hympanova, Jan Marek, Ondrej Soukup and Martin Hruby
Czech Academy of Sciences, Academy of Sciences of the Czech Republic, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Czech Academy of Sciences, University Hospital Hradec Kralove, University Hospital Hradec Kralove, University Hospital Hradec Kralove and Academy of Sciences of the Czech Republic
Downloads 31 (1,318,317)

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microparticles, pH-responsive, bacteria, microfluidics, vesicles, polymersomes