Author Page for Gordon H. Guyatt

The EAT-Lancet 2025 Report: Half A Decade Later, Key Methodological Issues Remain

The Lancet, volume 407, issue 10530, 2026[10.1016/S0140-6736(25)02509-7]

Number of pages: 4 Posted: 01 Dec 2025 Last Revised: 17 Mar 2026

Francisco J. Zagmutt, Jane G Pouzou, Flaminia Ortenzi, Gordon H. Guyatt, Andrew Mente and Ty Beal

EpiX Analytics, EpiX Analytics, Global Alliance for Improved Nutrition, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), David Braley Cardiac, Vascular and Stroke Research Institute (DBCVSRI) - Population Health Research Institute and Global Alliance for Improved Nutrition

Downloads 447 (160,805)

Citation 2

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2.

Pharmacotherapy for Overweight and Obese Adults: A Systematic Review and Network Meta-Analysis of Randomised Controlled Trials

Number of pages: 38 Posted: 01 Jun 2021

Qingyang Shi, Yang Wang, Qiukui Hao, Per Olav Vandvik, Gordon H. Guyatt, Jing Li, Zhe Chen, Shishi Xu, Yanjiao Shen, Long Ge, Feng Sun, Ling Li, Jiajie Yu, Kailei Nong, Xinyu Zou, Siyi Zhu, Cong Wang, Shengzhao Zhang, Zhi Qiao, Zhongyu Jian, Ya Li, Xinyi Zhang, Kerun Chen, Furong Qu, Yuan Wu, Yazhou He, Haoming Tian and Sheyu Li

Sichuan University - Department of Endocrinology and Metabolism, Sichuan University - Department of Endocrinology and Metabolism, McMaster University, Lovisenberg Diaconal Hospital - Department of Medicine, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), Sichuan University - Department of Endocrinology and Metabolism, Tianjin University of Traditional Chinese Medicine - Evidence-based Medicine Centre, Sichuan University - Department of Endocrinology and Metabolism, Cochrane China Centre - Department of Guideline and Rapid Recommendation, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), Peking University - Department of Epidemiology and Biostatistics, Cochrane China Centre - Department of Guideline and Rapid Recommendation, Cochrane China Centre - Department of Guideline and Rapid Recommendation, Sichuan University - Department of Endocrinology and Metabolism, Sichuan University - Department of Endocrinology and Metabolism, Xiamen University - Department of Computer Science, Sichuan University - Evidence-based Nursing Centre, Sichuan University - Department of Pharmacy, Sichuan University - West China College of Medicine, Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Sichuan University - West China School of Medicine, Sichuan University - Department of Endocrinology and Metabolism, Sichuan University - West China School of Medicine, Cochrane China Centre - Department of Guideline and Rapid Recommendation, Xi'an Jiaotong University (XJTU) - Department of Endocrinology and Metabolism, Sichuan University - West China School of Public Health, Sichuan University and Sichuan University - Department of Endocrinology and Metabolism

Downloads 385 (191,334)

Citation 4

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3.

Probiotics, Prebiotics, and Synbiotics for Prevention of Mortality and Morbidity in Preterm Infants: A Systematic Review and Network Meta-Analysis of Randomized Trials

Number of pages: 26 Posted: 19 Mar 2019

Behnam Sadeghirad, Ivan D. Florez, Rebecca L. Morgan, Farid Foroutan, Yaping Chang, Dena Zeraatkar, Malgorzata M. Bala, Shaneela Shahid, Taoying Lu, Long Ge, Joseph Beyene, Martin Offringa, Philip M. Sherman, Enas el Gouhary, Gordon H. Guyatt and Bradley Johnston

McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), Jagiellonian University in Krakow - Medical College, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), Guangzhou University of Chinese Medicine, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), University of Toronto - Child Health Evaluative Sciences, University of Toronto - The Hospital for Sick Children - SickKids, McMaster University - Faculty of Health Sciences, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI) and McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI)

Downloads 269 (282,737)

Citation 1

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4.

Shorter Versus Longer Duration of Antibiotic Treatment for Community-Acquired Pneumonia in Children: A Systematic Review and Meta-Analysis

Number of pages: 49 Posted: 25 Jul 2022

Ya Gao, Ming Liu, Kelu Yang, Yunli Zhao, Jinhui Tian, Jeffrey M. Pernica and Gordon H. Guyatt

Shandong University, Lanzhou University - Evidence-Based Medicine Center, KU Leuven - Department of Public Health and Primary Care, Sichuan University - National Clinical Research Center for Geriatrics, Lanzhou University - Evidence-Based Medicine Center, McMaster University - Health Research Methods, Evidence, and Impact and McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI)

Downloads 219 (348,255)

Abstract:

5.

Comparative Effects of Obesity Medications for Adults Living with Obesity: A Systematic Review and Network Meta-Analysis

Number of pages: 34 Posted: 14 Jul 2025

Sichuan University - Department of Endocrinology and Metabolism, University of Groningen, Sichuan University - Department of Endocrinology and Metabolism, University of Alberta, MAGIC Evidence Ecosystem Foundation, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), Shanghai Jiao Tong University (SJTU) - Institute and Department of Endocrinology and Metabolism, Sichuan University - Department of Endocrinology and Metabolism, University of Leicester - Leicester Diabetes Centre, University College Dublin (UCD) - Diabetes Complications Research Centre, Universitas Indonesia (UI), Sichuan University - Department of Endocrinology and Metabolism, Sichuan University, Sichuan University, McMaster University, TidalHealth, Sichuan University - Department of Endocrinology and Metabolism, Sichuan University - Department of Endocrinology and Metabolism, Lehigh Valley Health Network, Shandong Second Medical University, Shanghai Jiao Tong University (SJTU) - Institute and Department of Endocrinology and Metabolism, McMaster University, Sichuan University - Department of Endocrinology and Metabolism, Peking University - Department of Epidemiology and Biostatistics, Government of the People's Republic of China - Department of Hypertension and Endocrinology, University of Geneva - Geneva University Hospitals, Sichuan University - Department of Endocrinology and Metabolism, MAGIC Evidence Ecosystem Foundation and Sichuan University - Chinese Evidence-Based Medicine Centre

Downloads 146 (505,974)

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6.

Risk Factors for Hospitalization and Mortality in Patients with Influenza Virus Infection: A Systematic Review and Meta-Analysis

Number of pages: 45 Posted: 13 May 2025

Shandong University, Lanzhou University - Evidence-Based Medicine Center, Government of the United States of America - Centers for Disease Control and Prevention (CDC), St. Marianna University, Sichuan University, Chongqing Medical University, Central South University, Lanzhou University - The First Clinical Medical College, Sichuan University, Sichuan University, First People’s Hospital of Zigong, Northwest Minzu University, McMaster University, Lanzhou University, Lanzhou University - Evidence-Based Medicine Center, McMaster University, Shandong University, Beijing University of Chinese Medicine, Shandong University - Department of Biostatistics, Lanzhou University - Evidence-Based Social Science Research Center, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI) and McMaster University

Downloads 127 (569,079)

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7.

Grade Concept Article 5: Addressing Intransitivity in a Network Meta-Analysis

Number of pages: 23 Posted: 04 May 2023

Romina Brignardello Petersen, George A. Tomlinson, Ivan Florez, David M. Rind, Derek Chu, Rebeca L. Morgan, Reem Mustafa, Holger Schünemann and Gordon H. Guyatt

McMaster University, University Health Network, University of Antioquia, Institute for Clinical and Economic Review, McMaster University, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), University of Kansas, Humanitas University and McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI)

Downloads 127 (569,079)

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8.

Global Burden of Mpox-Associated Complications: A Systematic Review and Meta-Analysis

Number of pages: 37 Posted: 06 Aug 2025

Ya Gao, Gordon H. Guyatt, Wenshuo Zhao, Rongna Lian, Ming Liu, Yunli Zhao, Zhifan Li, Davy Ratovondramamy, Ping Liu, Wanyu Zhao, Kenji Numata, Wimonchat Tangamornsuksun, Fengwen Yang, Junhua Zhang, Fuzhong Xue, Jinhui Tian and Qiukui Hao

Shandong University, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), Shandong University, Sichuan University, Lanzhou University - Evidence-Based Medicine Center, Chongqing Medical University, Lanzhou University - The First Clinical Medical College, Shandong University, Chongqing Medical University, Sichuan University, St. Marianna University, McMaster University, Tianjin University of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine - Key Laboratory of National Medical Products Administration, Shandong University - Department of Biostatistics, Lanzhou University - Evidence-Based Social Science Research Center and McMaster University

Downloads 99 (694,528)

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9.

Operationalizing the GRADE-Equity Criterion to Inform Guideline Recommendations: Application to a Medical Cannabis Guideline

Number of pages: 27 Posted: 31 Mar 2023

Omar Dewidar, Jordi Pardo Pardo, Vivian Welch, Glen Hazlewood, Andrea J. Darzi, Cheryl Barnabe, Kevin Pottie, Jennifer Petkovic, Shawn Kuria, Samuel Sha, Sarah Allam, Jason W. Busse, Gordon H. Guyatt, Holger Schünemann and Peter Tugwell

Élisabeth Bruyere Research Institute, University of Ottawa, Élisabeth Bruyere Research Institute, University of Calgary, McMaster University, University of Calgary - Department of Community Health Sciences, Western University, University of Ottawa - Bruyère Research Institute, University of Ottawa, University of Ottawa, University of Ottawa - Bruyère Research Institute, McMaster University - Department of Anesthesia, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), Humanitas University and University of Ottawa

Downloads 99 (694,528)

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10.

An Innovative Modification of Grade's Minimally Contextualized Framework to Categorize Interventions in a Network Meta-Analysis

Number of pages: 14 Posted: 08 Jun 2022

Qingyang Shi, Gordon H. Guyatt, Qiukui Hao and Sheyu Li

Sichuan University - Department of Endocrinology and Metabolism, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University and Sichuan University - Chinese Evidence-Based Medicine Centre

Downloads 81 (796,622)

Citation 1

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11.

GRADE guidance: Strategies to enhance the utilization of randomized and non-randomized studies in evidence syntheses of health interventions

Number of pages: 27 Posted: 14 Sep 2025

Carlos A. Cuello-Garcia, Rebeca L. Morgan, Nancy Santesso, Pablo Alonso-Coello, Romina Brignardello-Petersen, Lukas Schwingshackl, Jan Brozek, Srinivasa Vittal Katikireddi, Zachary Munn, Hugh Sharma-Waddington, Kevin C. Wilson, Joerg Meerpohl, Daniel R. Morales, Ignacio Neumann, Peter Tugwell, Gordon H. Guyatt and Holger J. Schünemann

McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University, Sant Pau Biomedical Research Institute (IIB Sant Pau) - Iberoamerican Cochrane Centre - Department of Clinical Epidemiology and Public Health, McMaster University, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Glasgow - Institute of Health and Wellbeing, University of Adelaide - Faculty of Health and Medical Sciences, London School of Hygiene & Tropical Medicine, affiliation not provided to SSRN, University of Freiburg, University of Dundee, Pontificia Universidad Católica de Chile - Department of Internal Medicine, University of Ottawa, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI) and IRCCS Humanitas Research Hospital

Downloads 72 (860,052)

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12.

Amyloid-Beta (Aβ)-Targeting Agents for Mild to Moderate Alzheimer's Disease: Systematic Review and Meta-Analysis

Number of pages: 37 Posted: 10 Feb 2020

Liming Lu, Xiaoyan Zheng, Shengwen Wang, Yuqing Zhang, Gaolei Yao, Jingchun Zeng, Shuqi Ge, Hao Wen, Gordon H. Guyatt, Chunzhi Tang and Nenggui Xu

Guangzhou University of Chinese Medicine - Clinical Research and Data Center, Guangzhou University of Chinese Medicine - Clinical Research and Data Center, Sun Yat-sen University (SYSU), McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), Guangzhou University of Chinese Medicine - Clinical Research and Data Center, Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine - Clinical Research and Data Center, Guangzhou University of Chinese Medicine - Clinical Research and Data Center, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), Guangzhou University of Chinese Medicine - Clinical Research and Data Center and Guangzhou University of Chinese Medicine - Clinical Research and Data Center

Downloads 60 (961,006)

Abstract:

13.

Developing an Observer Instrument of the Occurrence of Shared Decision Making (SDMo): Sensitizing item generation and Delphi study

Number of pages: 38 Posted: 22 Oct 2025

Misk Al Zahidy, Victor Montori V., Madeline O'Grady, Michael R. Gionfriddo, Megan Branda, Ricardo Loor-Torres, Mayra Duran, Gordon H. Guyatt, Juan P. Brito, Victor M. Montori, Marleen Kunneman and Ian Hargraves

Mayo Clinic - Knowledge and Evaluation Research Unit, affiliation not provided to SSRN, affiliation not provided to SSRN, Mayo Clinic, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), Mayo Clinic, Mayo Clinic, Mayo Clinic and Mayo Clinic

Downloads 48 (1,086,013)

Abstract:

14.

A Novel Framework for Incorporating Patient Values and Preferences in Making Guideline Recommendations: Guideline Panel Surveys

Number of pages: 14 Posted: 10 Apr 2023

Linan Zeng, Lise M. Helsingen, Michael Bretthauer, Thomas Agoritsas, Per Olav Vandvik, Reem Mustafa, Jason Busse, Reed Siemieniu, Lyubov Lytvyn, Shelly-Anne Li, Mengting Yang, Lijiao Yan, Lingli Zhang, Romina Brignardello-Petersen and Gordon H. Guyatt

Sichuan University - Department of Pharmacy, University of Oslo - Clinical Effectiveness Research Group, University of Oslo - Clinical Effectiveness Group, University Hospitals of Geneva, Lovisenberg Diaconal Hospital - Department of Medicine, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University, McMaster University, McMaster University, University of Toronto, Sichuan University, Beijing University of Chinese Medicine, Sichuan University - Department of Pharmacy, McMaster University and McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI)

Downloads 42 (1,157,785)

Abstract:

15.

Limited consensus in expert opinions on studies evaluating the design, conduct, analysis, or reporting of health research: a survey study

Number of pages: 24 Posted: 18 Nov 2025

affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Toronto, The Ottawa Health Research Institute (OHRI), Brandenburg Medical School Theodor Fontane, University of Oxford, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), McMaster University, affiliation not provided to SSRN, McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), Catholic University of Croatia, Mayo Clinic, affiliation not provided to SSRN, University of Ottawa, University of Basel - University Hospital Basel, Élisabeth Bruyere Research Institute, affiliation not provided to SSRN, McMaster University, McMaster University and McMaster University

Downloads 40 (1,183,237)

Abstract:

16.

An Extension of the Anchor-Based MID Credibility Assessment Instrument Addressing Construct Proximity is a Reliable Alternative to the Correlation Item

Number of pages: 17 Posted: 07 Sep 2022

Yuting Wang, Tahira Devji, Alonso Carrasco-Labra, Anila Qasim, Qiukui Hao, Elena Kum, Niveditha Devasenapathy, Madeleine T. King, Berend Terluin, Caroline B. Terwee, Michael Walsh, Toshi A. Furukawa, Yasushi Tsujimoto and Gordon H. Guyatt

McMaster University - Health Research Methods, Evidence, and Impact, University of Toronto - Temerty Faculty of Medicine, University of Pennsylvania, McMaster University, McMaster University, McMaster University, University of New South Wales (UNSW) - The George Institute for Global Health, The University of Sydney - School of Psychology, VU University Amsterdam - Amsterdam Public Health Research Institute, VU University Amsterdam - Amsterdam Public Health Research Institute, McMaster University, Kyoto University - Department of Health Promotion and Human Behavior, Kyoto University - Department of Health Promotion and Human Behavior and McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI)

Downloads 35 (1,249,711)

Abstract:

17.

Developing methods guidance for health researchers: literature review of proposed and applied strategies

Number of pages: 56 Posted: 10 Apr 2026

Malena Chiaborelli, Julian Hirt, Matthias Briel, Frances Shiely, Anne-Laure Bouesteix, Gordon H. Guyatt, Frank Bretz, David Moher PhD, Derek Stewart and Stefan Schandelmaier

affiliation not provided to SSRN, University of Basel and University Hospital Basel, University of Basel - University Hospital Basel, University College Cork - TRAMS (Trial Research and Methodologies Unit), Ludwig Maximilian University of Munich (LMU), McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI), Independent, The Ottawa Health Research Institute (OHRI), Independent and University of Basel - University Hospital Basel

Downloads 33 (1,277,121)

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18.

Misusing I² for Inconsistency, Overlooking OIS for Imprecision, and Ignoring the Continuum of Certainty Ratings: Common Pitfalls in GRADE Assessments

Number of pages: 23 Posted: 12 Sep 2025

Prashanti Eachempati and Gordon H. Guyatt

MAGIC Evidence Ecosystem Foundation and McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI)

Downloads 31 (1,304,549)

Abstract:

19.

TITAN-SR: development and validation of a biomedical BERT ensemble for systematic-review screening

Number of pages: 19 Posted: 08 May 2026

Tyler Pitre, Dena Zeraatkar, John Granton, Jason W. Busse, Bram Rochwerg and Gordon H. Guyatt

University of Toronto, McMaster University, University of Toronto, McMaster University - Department of Anesthesia, McMaster University and McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI)

Downloads 16 (1,491,251)

Gordon H. Guyatt

McMaster University - Department of Health Research Methods, Evidence, and Impact (HEI)

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