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Alex Horsley

The University of Manchester - Wythenshawe Hospital

Southmoor Road

Manchester, M23 9LT

United Kingdom

SCHOLARLY PAPERS

5

DOWNLOADS

477

TOTAL CITATIONS

4

Scholarly Papers (5)

1.

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of ION-827359, an Antisense Oligonucleotide Inhibitor of ENaC, in Healthy Volunteers and Patients with Cystic Fibrosis: A Double-Blind, Placebo-Controlled, Dose-Escalation, Phase 1/2a Study

Number of pages: 30 Posted: 20 Apr 2022
University of Duisburg-Essen - Division of Cystic Fibrosis, Ionis Pharmaceuticals, Ionis Pharmaceuticals, The University of Manchester - Wythenshawe Hospital, Ionis Pharmaceuticals, Ionis Pharmaceuticals, Ionis Pharmaceuticals, Ionis Pharmaceuticals and Queen’s University Belfast - Department of Medicine, Health and Life Sciences
Downloads 123 (588,531)
Citation 4

Abstract:

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cystic fibrosis, epithelial sodium channels, pharmacokinetics, safety, forced expiratory volume in 1 second, ION-827359

2.

Lower Airway and Oral Microbiome Dysbiosis in Patients with Long COVID Post-Hospitalisation: A UK Multicentre, Prospective Cohort Study

Number of pages: 28 Posted: 25 Jun 2025
University of Dundee, University of Dundee, University of Dundee, University of Dundee, University of Dundee, University of Dundee, University of Leicester - Department of Health Sciences, University of Leicester - Institute for Lung Health, University of Leicester - Institute for Lung Health, University of Leicester - Institute for Lung Health, University Hospitals of Leicester NHS Trust, University of Leicester - Institute for Lung Health, University of Leicester - Institute for Lung Health, University of Leicester - Institute for Lung Health, University of Leicester - Institute for Lung Health, University of Leicester - Centre for Exercise and Rehabilitation Science, University of Leicester - Institute for Lung Health, University of Leicester, University of Leicester, University of Leicester, University of Edinburgh - Centre for Medical Informatics, University of Edinburgh - Centre for Medical Informatics, University of Edinburgh - Usher Institute, University of Edinburgh - Asthma UK Centre for Applied Research, Imperial College London - National Heart and Lung Institute, University of Edinburgh - Usher Institute, University of Edinburgh, London School of Hygiene & Tropical Medicine, Imperial College London, University of Oxford, Imperial College London - National Heart and Lung Institute, King's College London - Institute of Psychiatry, Psychology & Neuroscience, University of Leicester - Leicester Diabetes Centre, Newcastle University - Population Health Sciences Institute, University of Oxford, University of Liverpool, Imperial College London - Hammersmith Hospital, University College London, Imperial College London - National Heart and Lung Institute, University Hospitals of Leicester NHS Trust, University of Leicester - NIHR Leicester Biomedical Research Centre, University of Oxford - Oxford Centre for Clinical Magnetic Resonance Research (OCMR), Imperial College London - National Heart and Lung Institute (NHLI), University College London - Centre for inflammation and Tissue Repair, Queen's University Belfast, University of Cambridge, Royal Papworth HospitalUniversity of Cambridge - Heart and Lung Research Institute, University of Sheffield, MRC-University of Glasgow Centre for Virus Research, University of Liverpool - Health Protection Research Unit in Emerging and Zoonotic Infections, University of Leicester - Centre for Exercise and Rehabilitation Science, NHS Foundation Trust - St. Georges University Hospitals, Leeds Teaching Hospitals NHS Trust, University of Nottingham, University College London, University of Edinburgh, The University of Manchester, Infection Research Group, Hull University Teaching Hospitals NHS Foundation Trust, Newcastle University, University of Cambridge, Guy's and St Thomas' NHS Foundation Trust, University College London, School of Life and Medical Sciences, Faculty of Medical Sciences, Division of Medicine, UCL Respiratory, University of Southampton - Department of Clinical and Experimental Sciences, University of Birmingham, Queen Mary University of London - Institute of Population Health Sciences, University of Oxford, University of Sheffield, King’s College London, Liverpool University Hospitals NHS Foundation Trust, Swansea University - College of Human and Health Sciences, Queen's University Belfast, Government of the United Kingdom - Oxford Interstitial Lung Disease Service, The University of Manchester - Wythenshawe Hospital, London School of Hygiene & Tropical Medicine - Department of Clinical Research, Asthma and Lung UK, University of Oxford - Oxford Centre for Clinical Magnetic Resonance Research (OCMR), University of Leicester - Department of Health Sciences, University of Leicester - Institute for Lung Health, University of Leicester - Institute for Lung Health, Imperial College London - National Heart and Lung Institute and University of Dundee - Division of Molecular and Clinical Medicine
Downloads 120 (608,822)

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3.

Residual Lung Abnormality Following COVID-19 Hospitalisation is Characterised by Epithelial Injury

Number of pages: 23 Posted: 17 Apr 2024
Imperial College London - National Heart and Lung Institute, University College London, University College London - Centre for inflammation and Tissue Repair, University of Leicester - Department of Health Sciences, The University of Manchester - Manchester University NHS Foundation Trust, Ulster University, University College London - Centre for inflammation and Tissue Repair, Imperial College London, Government of the United Kingdom - Royal Brompton and Harefield NHS Foundation Trust, University of Leicester, University of Leicester, University of Nottingham, Government of the United Kingdom - Oxford Interstitial Lung Disease Service, Asthma and Lung UK, University of Nottingham, University of Southampton - Department of Clinical and Experimental Sciences, University Hospitals of Leicester NHS Trust, University College London, Imperial College London, Imperial College London - National Heart and Lung Institute, University of Leicester, The University of Manchester, University College London, Imperial College London, The University of Manchester, University of Sheffield, Imperial College London, Liverpool University Hospitals NHS Foundation Trust, NHS Foundation Trust - Aintree University Hospital, The University of Manchester - Manchester University NHS Foundation Trust, University of Sheffield, Guy’s and St Thomas’ NHS Foundation Trust, University of Sheffield, Liverpool University Hospitals NHS Foundation Trust, University of Edinburgh - Centre for Medical Informatics, Oxford University Hospitals NHS Foundation Trust, University of Liverpool, University of Edinburgh - Centre for Medical Informatics, University of Edinburgh - Asthma UK Centre for Applied Research, Imperial College London - National Heart and Lung Institute, Sysmex R&D Centre UK, Sysmex R&D Centre UK, Sysmex R&D Centre UK, Sysmex R&D Centre UK, University of Leicester - Institute for Lung Health, University Hospitals of Leicester NHS Trust, University of Leicester - Institute for Lung Health, University of Leicester - Institute for Lung Health, University of Leicester - Institute for Lung Health, University of Oxford - Oxford Centre for Clinical Magnetic Resonance Research (OCMR), Asthma and Lung UK, University of Leicester - Institute for Lung Health, London School of Hygiene & Tropical Medicine - Department of Clinical Research, University of Leicester - Department of Health Sciences, University of Leicester - Centre for Exercise and Rehabilitation Science, The University of Manchester - Wythenshawe Hospital, University of Leicester - Institute for Lung Health, University of Leicester - Institute for Lung Health, University of Leicester - Institute for Lung Health, University of Leicester - Institute for Lung Health, University of Dundee - Division of Molecular and Clinical Medicine, University of Leicester - Institute for Lung Health, University College London, University of Leicester - Department of Health Sciences, Imperial College London - National Heart and Lung Institute and Independent
Downloads 118 (608,822)

Abstract:

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COVID-19, hospitalisation, lung, biomarker

4.

Breathlessness in Long COVID: Exploring the Relationship between Symptoms, Lung Function Tests, and Functional Imaging Using Hyperpolarised Xenon MRI

Number of pages: 24 Posted: 23 Jul 2025
University of Sheffield, University of Sheffield, University of Sheffield, University of Oxford, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, University of Oxford, University of Sheffield, University of Sheffield, University of Sheffield, University of Sheffield, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, University of Oxford, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, University of Sheffield, University of Sheffield, University of Sheffield, Cardiff and Vale University Health Board, University of Sheffield, University of Sheffield, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, Dept Infection, Immunity & Cardiovascular Disease, University of Sheffield, University of Sheffield, Manchester University NHS Trust, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, University of Sheffield, University of Sheffield, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, University of Oxford, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, University of Sheffield, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust, The University of Manchester - Wythenshawe Hospital, Cardiff and Vale University Hospitals NHS Trust, University of Sheffield, Oxford University Hospitals NHS Foundation Trust, University of Sheffield and Government of the United Kingdom - Oxford University Hospitals NHS Foundation Trust
Downloads 70 (891,180)

Abstract:

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Long COVID, Hyperpolarised Xenon MRI, Functional Imaging, Breathlessness, Never Hospitalised, Post-COVID-19 Condition

5.

Microbial Culture Underestimates Lung Pathogen Detection and Surveillance in Cystic Fibrosis

Number of pages: 16 Posted: 08 Jul 2021
Manchester Metropolitan University, Manchester Metropolitan University, Manchester Metropolitan University, The University of Manchester - Manchester University NHS Foundation Trust, The University of Manchester - Manchester University NHS Foundation Trust, The University of Manchester - Wythenshawe Hospital and Manchester Metropolitan University - Department of Life Sciences
Downloads 46 (1,109,210)

Abstract:

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