default author photo

Naomi Coombes

Public Health England - National Infection Service

United Kingdom

SCHOLARLY PAPERS

3

DOWNLOADS

170

TOTAL CITATIONS

11

Scholarly Papers (3)

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

Number of pages: 58 Posted: 01 Jun 2020
University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, Public Health England - National Infection Service, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - MRC Human Immunology Unit, University of Oxford - MRC Human Immunology Unit, Public Health England - National Infection Service, Public Health England - National Infection Service, Public Health England - National Infection Service, Diamond Light Source, Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, Public Health England - National Infection Service, University of Oxford - MRC Human Immunology Unit, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology and Weizmann Institute of Science - Department of Biomolecular Sciences
Downloads 46 (1,131,842)
Citation 3

Abstract:

Loading...

SARS-CoV-2, Spike, X-ray crystallography, Cryo-EM, Neutralisation, Monoclonal antibody, neutralising monoclonal antibody, COVID-19

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

Number of pages: 53 Posted: 12 May 2020
University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, Public Health England - National Infection Service, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - MRC Human Immunology Unit, University of Oxford - MRC Human Immunology Unit, Public Health England - National Infection Service, Public Health England - National Infection Service, Diamond Light Source, Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, Public Health England - National Infection Service, University of Oxford - MRC Human Immunology Unit, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology and Weizmann Institute of Science - Department of Biomolecular Sciences
Downloads 44 (1,157,169)
Citation 1

Abstract:

Loading...

Covid-19, SARS-CoV-2, Antibody Structure, Spike, Receptor Binding Domain, Neutralisation, Therapeutic Antibody, Crystallography, Cryo-EM, virus structure

2.

­­­The Antigenic Anatomy of SARS-CoV-2 Receptor Binding Domain

Number of pages: 87 Posted: 23 Dec 2020
University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Division of Structural Biology, Diamond Light Source Ltd - Harwell Science & Innovation Campus, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, Washington University in St. Louis - Department of Medicine, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, Washington University in St. Louis - Department of Medicine, Washington University in St. Louis - Department of Pathology and Immunology, Washington University School of Medicine - Department of Medicine, Washington University in St. Louis - Department of Medicine, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Department of Zoology, University of Oxford - MRC Human Immunology Unit, University of Oxford - Sir William Dunn School of Pathology, University of Oxford - Sir William Dunn School of Pathology, Public Health England - National Infection Service, Public Health England - National Infection Service, University of Oxford - Wellcome Centre for Human Genetics, Oxford University Hospitals NHS Foundation TrustUniversity of Oxford - Nuffield Department of Clinical Neurosciences, University of Oxford - Oxford Vaccine Group, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), Worthing Hospital, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Oxford Vaccine Group, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Peter Medawar Building for Pathogen Research, University of Kent - Viral Pseudotype Unit, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, University of Oxford - MRC Human Immunology Unit, Chang Gung University - Research Center for Emerging Viral Infections, University of Oxford - Division of Structural Biology, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), Washington University School of Medicine - Department of Medicine, University of Oxford - Division of Structural Biology, Weizmann Institute of Science - Department of Biomolecular Sciences and University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI)
Downloads 65 (916,100)
Citation 7

Abstract:

Loading...

SARS-CoV-2, antibody, germline, V-gene, receptor-binding-domain, spike, neutralisation, protection, glycosylation, valency

3.

A modified vaccinia Ankara (MVA) virus vectored Zika vaccine that generates neutralising antibodies and potent T cell responses in type I interferon deficient mice

Number of pages: 35 Posted: 30 Jun 2026
University of Liverpool - Department of Clinical Infection Microbiology and Immunology, University of Liverpool, University of Liverpool, affiliation not provided to SSRN, affiliation not provided to SSRN, Public Health England - National Infection Service, UK Health Security Agency, University of Liverpool - Department of Clinical Infection, Microbiology and Immunology, University of Liverpool - Institute of Infection, Veterinary and Ecological Sciences, Public Health England - National Infection Service, University of Liverpool, University of Liverpool - Institute of Infection, Veterinary and Ecological Sciences, Ludwig Maximilian University of Munich (LMU), University of Oxford - Wellcome Trust Centre for Human Genetics, University of Liverpool, University of Liverpool and University of Liverpool - NIHR Health Protection Research Unit in Emerging and Zoonotic Infections
Downloads 15

Abstract:

Loading...

Zika virus, modified vaccinia Ankara (MVA), T cells, antibodies, Vaccine, A129 mice